Unusual histopathological findings in appendectomy specimens from patients with suspected acute appendicitis

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dc.authoridKutluturk, Koray/0000-0002-7030-4953
dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridYILMAZ, Mehmet/0000-0002-5710-5263
dc.authorwosidYilmaz, Mehmet/AAF-6095-2021
dc.authorwosidKutluturk, Koray/S-5493-2019
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidYILMAZ, Mehmet/HKM-4739-2023
dc.contributor.authorYilmaz, Mehmet
dc.contributor.authorAkbulut, Sami
dc.contributor.authorKutluturk, Koray
dc.contributor.authorSahin, Nurhan
dc.contributor.authorArabaci, Ebru
dc.contributor.authorAra, Cengiz
dc.contributor.authorYilmaz, Sezai
dc.date.accessioned2024-08-04T20:37:43Z
dc.date.available2024-08-04T20:37:43Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAIM: To investigate the prevalence and implications of unusual histopathological findings in appendectomy specimens from patients with suspected acute appendicitis. METHODS: The demographic and histopathological data of 1621 patients (>= 16 years-old) who underwent appendectomy to treat an initial diagnosis of acute appendicitis between January 1999 and November 2011 were retrospectively assessed. Microscopic findings were used to classify the patients under six categories: appendix vermiformis, phlegmonous appendicitis, gangrenous appendicitis, perforated appendicitis, supurative appendicitis, and unusual histopathologic findings. The demographic and clinicopathologic characteristics of patients with unusual histopathologic findings were evaluated in detail, and re-analysis of archived resected appendix specimens was carried out. RESULTS: A total of 912 males and 709 females, from 16 to 94 years old, were included in the study and comprised 789 cases of suppurative appendicitis, 370 cases of appendix vermiformis, 243 cases of perforated gangrenous appendicitis, 53 cases of flegmaneous appendicitis, 32 cases of gangrenous appendicitis, and 134 (8.3%) cases of unusual histopathological findings. The unusual histopathological findings included fibrous obliteration (n = 62), enterobius vermicularis (n = 31), eosinophilic infiltration (n = 10), mucinous cystadenoma (n = 8), carcinoid tumor (n = 6), granulomatous inflammation (n = 5), adenocarcinoma (n = 4; one of them mucinous), and mucocele (n = 3), adenomatous polyp (n = 1), taenia sup (n = 1), ascaris lumbricoides (n = 1), appendiceal diverticula (n = 1), and B cell non-hodgkin lymphoma (n = 1). None of the 11 patients with subsequent diagnosis of tumor were suspected of cancer prior to the appendectomy. CONCLUSION: Even when the macroscopic appearance of appendectomy specimens is normal, histopathological assessment will allow early diagnosis of many unusual diseases. (C) 2013 Baishideng. All rights reserved.en_US
dc.identifier.doi10.3748/wjg.v19.i25.4015
dc.identifier.endpage4022en_US
dc.identifier.issn1007-9327
dc.identifier.issn2219-2840
dc.identifier.issue25en_US
dc.identifier.pmid23840147en_US
dc.identifier.scopus2-s2.0-84880077624en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage4015en_US
dc.identifier.urihttps://doi.org/10.3748/wjg.v19.i25.4015
dc.identifier.urihttps://hdl.handle.net/11616/96130
dc.identifier.volume19en_US
dc.identifier.wosWOS:000321514000013en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBaishideng Publishing Group Incen_US
dc.relation.ispartofWorld Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAppendicitisen_US
dc.subjectAppendectomy specimensen_US
dc.subjectHistopathologyen_US
dc.subjectUnusual findingsen_US
dc.subjectAppendiceal malignancyen_US
dc.titleUnusual histopathological findings in appendectomy specimens from patients with suspected acute appendicitisen_US
dc.typeArticleen_US

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