Early neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society

dc.authoridCan, Emrah/0000-0002-2163-6564
dc.authoridGursoy, Tugba/0000-0002-6084-4067
dc.authoridCalkavur, Sebnem/0000-0002-3820-2690
dc.authoridOkulu, Emel/0000-0002-1101-3355
dc.authoridTuran, Ozden/0000-0002-7707-1881
dc.authoridÇETİNKAYA, BİLİN/0000-0003-0866-7339
dc.authoridUygur, Ozgun/0000-0002-7580-915X
dc.authorwosidCetinkaya, Merih/AFP-9671-2022
dc.authorwosidCan, Emrah/J-1528-2015
dc.authorwosidGursoy, Tugba/AGO-5295-2022
dc.authorwosidCalkavur, Sebnem/JGE-3009-2023
dc.authorwosidIsik, Dilek Ulubas/V-5657-2017
dc.authorwosidÖrs, Rahmi/A-4735-2016
dc.authorwosidOzdemir, Ahmet/GPX-3489-2022
dc.contributor.authorKoc, Esin
dc.contributor.authorDemirel, Nihal
dc.contributor.authorBas, Ahmet Yagmur
dc.contributor.authorIsik, Dilek Ulubas
dc.contributor.authorHirfanoglu, Ibrahim Murat
dc.contributor.authorTunc, Turan
dc.contributor.authorSari, Fatma Nur
dc.date.accessioned2024-08-04T20:47:02Z
dc.date.available2024-08-04T20:47:02Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from neonatal intensive care units (NICUs) in Turkey. Material and methods A prospective cohort study was performed between April 1, 2016 and April 30, 2017. The study included VLBW infants admitted to level III NICUs. Perinatal and neonatal data of all infants born with a birth weight of.1500 g were collected for infants who survived. Results Data from 69 NICUs were obtained. The mean birth weight and gestational age were 1137 +/- 245 g and 29 +/- 2.4 weeks, respectively. During the study period, 78% of VLBW infants survived to discharge and 48% of survived infants had no major neonatal morbidity. VLBW infants who survived were evaluated in terms of major morbidities: bronchopulmonary dysplasia was detected in 23.7% of infants, necrotizing enterocolitis in 9.1%, blood culture proven late-onset sepsis (LOS) in 21.1%, blood culture negative LOS in 21.3%, severe intraventricular hemorrhage in 5.4% and severe retinopathy of prematurity in 11.1%. Hemodynamically significant patent ductus arteriosus was diagnosed in 24.8% of infants. Antenatal steroids were administered to 42.9% of mothers. Conclusion The present investigation is the first multicenter study to include epidemiological information on VLBW infants in Turkey. Morbidity rate in VLBW infants is a serious concern and higher than those in developed countries. Implementation of oxygen therapy with appropriate monitoring, better antenatal and neonatal care and control of sepsis may reduce the prevalence of neonatal morbidities. Therefore, monitoring standards of neonatal care and implementing quality improvement projects across the country are essential for improving neonatal outcomes in Turkish NICUs.en_US
dc.description.sponsorshipTurkish Neonatal Society [2-2016]; Turkish Neonatal Societyen_US
dc.description.sponsorshipThis study was supported by the Turkish Neonatal Society, http://www.neonatology.org.tr, number 2-2016, received by AYB. Turkish Neonatal Society funded the study's online registry system. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.en_US
dc.identifier.doi10.1371/journal.pone.0226679
dc.identifier.issn1932-6203
dc.identifier.issue12en_US
dc.identifier.pmid31851725en_US
dc.identifier.scopus2-s2.0-85076709481en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0226679
dc.identifier.urihttps://hdl.handle.net/11616/99106
dc.identifier.volume14en_US
dc.identifier.wosWOS:000534242500056en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPublic Library Scienceen_US
dc.relation.ispartofPlos Oneen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBronchopulmonary Dysplasiaen_US
dc.subjectNecrotizing Enterocolitisen_US
dc.subjectMorbidityen_US
dc.subjectMortalityen_US
dc.subjectHealthen_US
dc.subjectPrematurityen_US
dc.subjectInfectionsen_US
dc.subjectCountriesen_US
dc.subjectDistressen_US
dc.subjectSepsisen_US
dc.titleEarly neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Societyen_US
dc.typeArticleen_US

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