LIVING DONOR LIVER TRANSPLANTATION FOR HEPATIC EPITHELIOID HEMANGIOENDOTHELIOMA: SINGLE CENTER EXPERIENCE

dc.contributor.authorErsan, Veysel
dc.contributor.authorInce, Volkan
dc.contributor.authorUsta, Sertaç
dc.contributor.authorBarut, Bora
dc.contributor.authorSamdancı, Emine
dc.contributor.authorCarr, Brian
dc.contributor.authorYılmaz, Sezai
dc.date.accessioned2024-08-04T19:53:08Z
dc.date.available2024-08-04T19:53:08Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: Hepatic epithelioid hemangioendothelioma (HEHE) is a rare malignant vascular tumor of the liver. Liver transplantation (LT) is the treatment of choice for patients with advanced-stage HEHE. The aim of this study is to present the results of HEHE patients treated with living donor LT. Material and Method : Between March 2002 and December 2021, 3121 liver transplantations were performed at our institute, 2632 of these were living donor LT. Demographic characteristics, symptoms and clinical findings, laboratory, radiological, and posttransplant histopathological examinations, recurrence rates, disease-free survival, and overall survival rates of the patients were analyzed. Results: The mean age was 41.7 years and %57.6 of the patients were women. Five patients were referred to our institute with signs of chronic liver failure. Four of these patients (57.1%) had Budd-Chiari syndrome. The median follow-up was 35.0 (12.8 - 119.4) months. In all patients, the tumor recurrence rate after transplantation was 71.4%. The overall survival rate for 1 and 5 years was 100 – 57.1% and the disease free survival rate for 1 and 5 years was 71.4 - 38.1%, respectively. Conclusion: Living donor liver transplantation can be considered a viable treatment option for selected HEHE patients. However, multicenter collaborations are crucial to enhance our understanding of this rare malignancy and improve treatment outcomes for these patients.en_US
dc.identifier.endpage372en_US
dc.identifier.issn1305-5151
dc.identifier.issn2148-6190
dc.identifier.issue4en_US
dc.identifier.startpage365en_US
dc.identifier.trdizinid1250421en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1250421
dc.identifier.urihttps://hdl.handle.net/11616/89477
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofİzmir Eğitim ve Araştırma Hastanesi Tıp Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleLIVING DONOR LIVER TRANSPLANTATION FOR HEPATIC EPITHELIOID HEMANGIOENDOTHELIOMA: SINGLE CENTER EXPERIENCEen_US
dc.typeArticleen_US

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