The evaluation of thyroid nodules is routine use of frozen section examination necessary followingpreoperative fine needle aspiration biopsy
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Dosyalar
Tarih
2003
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Kulak Burun Bogaz Ihtisas Dergisi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Ameliyat öncesi ince i¤ne aspirasyon biyopsisi
(‹‹AB) sonuçlar›n› tek parametre olarak kullanarak tiroidektominin
geniflli¤ine karar verilip verilemeyece¤i ve
frozen section incelemesinin her olguda rutin olarak
gerekip gerekmedi¤i araflt›r›ld›.
Hastalar ve Yöntemler: Çal›flmaya nodüler tiroit tan›s›yla
tiroidektomi ameliyat› yap›lan ve ameliyat öncesinde
ince i¤ne aspirasyonu (n=46) ve/veya ameliyat
s›ras›nda frozen section (n=40) sonuçlar›na ula-
fl›labilen 67 hasta (40 kad›n, 27 erkek; ort. yafl 44;
da¤›l›m 17-78) al›nd›. ‹ki yöntemin sonuçlar›yla patolojik
inceleme sonuçlar› karfl›laflt›r›ld›.
Bulgular: Histopatolojik sonuçlar 25 olguda (%37.3)
malign, 42 olguda (%62.7) benign bulundu. ‹nce i¤-
ne aspirasyon biyopsisinin duyarl›l›¤› %50, özgüllü-
¤ü %95, tan›sal do¤ruluk oran› %77; frozen section
incelemesinin duyarl›l›¤› %100, özgüllü¤ü %87, tan›-
sal do¤rulu¤u %91 bulundu.
Sonuç: Bulgular›m›z, ‹‹AB’nin düflük duyarl›l›k ve tan›-
sal do¤ruluk de¤erleri nedeniyle, klinik malignensi parametrelerinin
dikkatle de¤erlendirilmesi ile birlikte rutin
frozen section incelemesinin gerekli oldu¤unu göstermektedir.
We evaluated the role of fine-needle aspiration biopsy as a single parameter in determining the extent of thyroidectomy and the necessity of routine use of frozen-section examination in patients with nodular thyroid disease. Pat i ents and Methods: We reviewed 67 patients (40 females, 27 males; mean age 44 years; range 17 to 78 years) who underwent thyroidectomy for nodular thyroid disease. Preoperative fine-needle aspiration biopsy and intraoperative frozen-section examination were performed in 46 patients and 40 patients, respectively. The results were compared with histopathologic diagnoses. Results: Histopathologically, 25 patients (37.3%) had malignant and 42 patients (62.7%) had benign disease. The sensitivity, specificity, and diagnostic accuracy were 50%, 95%, and 77% for fine-needle aspiration biopsy, and 100%, 87%, and 91% for frozen-section examination, respectively. Conclusion: In view of lower sensitivity and accuracy rates for fine-needle aspiration biopsy, the routine use of frozen-section examination seems to be necessary especially in cases with highly suggestive clinical findings of malignancy.
We evaluated the role of fine-needle aspiration biopsy as a single parameter in determining the extent of thyroidectomy and the necessity of routine use of frozen-section examination in patients with nodular thyroid disease. Pat i ents and Methods: We reviewed 67 patients (40 females, 27 males; mean age 44 years; range 17 to 78 years) who underwent thyroidectomy for nodular thyroid disease. Preoperative fine-needle aspiration biopsy and intraoperative frozen-section examination were performed in 46 patients and 40 patients, respectively. The results were compared with histopathologic diagnoses. Results: Histopathologically, 25 patients (37.3%) had malignant and 42 patients (62.7%) had benign disease. The sensitivity, specificity, and diagnostic accuracy were 50%, 95%, and 77% for fine-needle aspiration biopsy, and 100%, 87%, and 91% for frozen-section examination, respectively. Conclusion: In view of lower sensitivity and accuracy rates for fine-needle aspiration biopsy, the routine use of frozen-section examination seems to be necessary especially in cases with highly suggestive clinical findings of malignancy.
Açıklama
Anahtar Kelimeler
Biyopsi, İğne, Frozen section, Duyarlılık ve özgüllük, Tiroit hastalıkları/tanı, Tiroit bezi/patoloji/cerrahi, Tiroit neoplazmları/tanı, Tiroit nodülü/patoloji/tedavi, Tiroidektomi, Biopsy, Needle, Frozen sections, Sensitivity and specificity, Thyroid diseases/diagnosis, Thyroid gland/pathology/surgery, Thyroid neoplasms/diagnosis, Thyroid nodule/ pathology/therapy, Thyroidectomy
Kaynak
Kulak Burun Bogaz Ihtisas Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
11
Sayı
3
Künye
Saydam, L. Kalcıoğlu, M. T. Kızılay, A. Bozkurt, M. K. (2003). The evaluation of thyroid nodules is routine use of frozen section examination necessary followingpreoperative fine needle aspiration biopsy. Kulak Burun Bogaz Ihtisas Dergisi. 11(3):80-84.
