Rose oil inhalation protects against formaldehyde-induced testicular damage in rats

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dc.authoridKose, Evren/0000-0002-0246-2589
dc.authoridOgeturk, Murat/0000-0002-5744-4812
dc.authoridDabak, Durrin O/0000-0001-7210-6873
dc.authoridTurk, Gaffari/0000-0001-7417-1038
dc.authorwosidKose, Evren/ABG-9908-2020
dc.authorwosidOgeturk, Murat/B-3444-2008
dc.authorwosidKAVAKLI, AHMET/V-8005-2018
dc.authorwosidDabak, Durrin O/W-6090-2018
dc.authorwosidTürk, Gaffari/V-6922-2018
dc.contributor.authorKose, E.
dc.contributor.authorSarsilmaz, M.
dc.contributor.authorTas, U.
dc.contributor.authorKavakli, A.
dc.contributor.authorTurk, G.
dc.contributor.authorDabak, D. Ozlem
dc.contributor.authorSapmaz, H.
dc.date.accessioned2024-08-04T20:35:54Z
dc.date.available2024-08-04T20:35:54Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this experimental study, harmful effects of formaldehyde (FA) inhalation on sperm concentration, sperm quality, serum testosterone levels and the rat testes were investigated. In addition, the possible protective effects of rose oil against to these harmful effects were evaluated. For this purpose, 21 albino-Wistar rats were used. The rats in Group I were used as control group. When the rats of Group II were exposed FA (10 ppm/1 h) for 35 days, the rats of Group III inhalated rose oil (1 ml/1 h) after FA. The epididymal tissues were taken for sperm analysing and the testes were removed for histological examination. In addition, testosterone levels were determined from the blood samples. Although the testosterone levels, the epididymal sperm concentration, and the progressive sperm motility significantly decreased, the abnormal sperm rate significantly increased in the Group II when compared to Group I. In the Group III, these damages were seen less. When the rats in the Group II compared with the control group, there were serious histological damages. In the Group III, it was determined that the histological changes were less than group II. It can be expressed that serious damages occurred via formaldehyde exposure in male reproductive system and that the rose oil had protective effects against these damages.en_US
dc.description.sponsorshipThe Firat University Research Foundation [FUBAP-1286]en_US
dc.description.sponsorshipThis work was supported by The Firat University Research Foundation (FUBAP-1286).en_US
dc.identifier.doi10.1111/j.1439-0272.2011.01187.x
dc.identifier.endpage348en_US
dc.identifier.issn0303-4569
dc.identifier.issn1439-0272
dc.identifier.pmid21749434en_US
dc.identifier.scopus2-s2.0-84861506867en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage342en_US
dc.identifier.urihttps://doi.org/10.1111/j.1439-0272.2011.01187.x
dc.identifier.urihttps://hdl.handle.net/11616/95669
dc.identifier.volume44en_US
dc.identifier.wosWOS:000304439300047en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAndrologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFormaldehydeen_US
dc.subjectraten_US
dc.subjectrose oilen_US
dc.subjectspermen_US
dc.subjecttestesen_US
dc.titleRose oil inhalation protects against formaldehyde-induced testicular damage in ratsen_US
dc.typeArticleen_US

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