Hemolytic uremic syndrome outbreak in Turkey in 2011

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dc.authoridGulleroglu, Kaan/0000-0003-1434-3824
dc.authoridDursun, Hasan/0000-0002-8817-494X
dc.authoridCanpolat, Nur/0000-0002-3420-9756
dc.authoridGulleroglu, Kaan/0000-0003-1434-3824
dc.authoridözkaya, ozan/0000-0002-0198-1221
dc.authoridIsiyel, Emel/0000-0001-9364-6473
dc.authoridDincel, Nida/0000-0002-1179-8519
dc.authorwosidGulleroglu, Kaan/F-3294-2013
dc.authorwosidDursun, Hasan/AAW-8783-2020
dc.authorwosidDursun, Hasan/AAB-7105-2020
dc.authorwosidCanpolat, Nur/AHE-2082-2022
dc.authorwosidGulleroglu, Kaan/AAJ-8833-2021
dc.authorwosidTabel, Yilmaz/AAF-9801-2020
dc.authorwosidözkaya, ozan/AAO-2136-2020
dc.contributor.authorEkinci, Zelal
dc.contributor.authorCandan, Cengiz
dc.contributor.authorAlpay, Harika
dc.contributor.authorCanpolat, Nur
dc.contributor.authorAkyuz, Sare Gulfem
dc.contributor.authorGunduz, Zubeyde
dc.contributor.authorDursun, Ismail
dc.date.accessioned2024-08-04T20:37:51Z
dc.date.available2024-08-04T20:37:51Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this retrospective multicenter study was to define the epidemiological and clinical features and prognostic factors of the first diarrhea-related hemolytic uremic syndrome (D+HUS) outbreak in Turkey in 2011. All pediatric nephrology centers in Turkey were asked about D+HUS patients via e-mail. Seventy D+HUS patients (median age: 5.7 years) participated. The seasonal peak was around the 7th, 8th and 9th months with 44 cases, centered in the east Marmara region. No causative agent could be identified. The rate of neurological complications and mortality was 21.4% and 4.2%, respectively. Eculizumab was used in four cases. Two of them had severe neurological complications despite plasma exchange. Elevated polymorphonuclear leukocyte count during hospital admission was the predictor of both severe disease and poor outcome. Duration of prodrome was the predictor of poor outcome (p<0.05). In conclusion, the median age of the affected children was greater than in the previous reports, while clinical features and outcome were similar.en_US
dc.identifier.endpage252en_US
dc.identifier.issn0041-4301
dc.identifier.issue3en_US
dc.identifier.pmid24217069en_US
dc.identifier.scopus2-s2.0-84883872952en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage246en_US
dc.identifier.urihttps://hdl.handle.net/11616/96202
dc.identifier.volume55en_US
dc.identifier.wosWOS:000341414400002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish J Pediatricsen_US
dc.relation.ispartofTurkish Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecthemolytic uremic syndromeen_US
dc.subjectdiarrhea-relateden_US
dc.subjectoutbreaken_US
dc.subjectchildrenen_US
dc.subjectepidemiologyen_US
dc.subjecteculizumaben_US
dc.titleHemolytic uremic syndrome outbreak in Turkey in 2011en_US
dc.typeArticleen_US

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