Chylous ascites after liver transplantation: Incidence and risk factors

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dc.authoridYILMAZ, Mehmet/0000-0002-5710-5263
dc.authoridOzdemir, Fatih/0000-0003-0292-3602
dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authoridÖZDEMİR, FATİH/0000-0003-0292-3602
dc.authoridIsik, Burak/0000-0002-2395-3985
dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authorwosidYILMAZ, Mehmet/HKM-4739-2023
dc.authorwosidOzdemir, Fatih/ABH-2875-2020
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidKayaalp, Cuneyt/AAH-1764-2021
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.authorwosidÖZDEMİR, FATİH/HJI-7585-2023
dc.authorwosidYilmaz, Mehmet/AAF-6095-2021
dc.contributor.authorYilmaz, Mehmet
dc.contributor.authorAkbulut, Sami
dc.contributor.authorIsik, Burak
dc.contributor.authorAra, Cengiz
dc.contributor.authorOzdemir, Fatih
dc.contributor.authorAydin, Cemalettin
dc.contributor.authorKayaalp, Cuneyt
dc.date.accessioned2024-08-04T20:36:06Z
dc.date.available2024-08-04T20:36:06Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, we evaluated the diagnosis, epidemiology, risk factors, and treatment of chylous ascites developing after liver transplantation (LT). Between 2002 and 2011, LT was performed 693 times in 631 patients at our clinic. One-hundred fifteen of these patients were excluded for reasons such as retransplantation, early postoperative mortality, and insufficient data. Chylous ascites developed after LT (mean +/- SD = 8.0 +/- 3.2 days, range = 5-17 days) in 24 of the 516 patients included in this study. Using univariate and multivariate analyses, we examined whether the following were risk factors for developing chylous ascites: age, sex, body mass index, graft-to-recipient weight ratio, Model for End-Stage Liver Disease score, vena cava cross-clamping time, total operation time, Child-Pugh classification, sodium level, portal vein thrombosis or ascites before transplantation, donor type, albumin level, and perihepatic dissection technique [LigaSure vessel sealing system (LVSS) versus conventional suture ligation]. According to a univariate analysis, a low albumin level (P = 0.04), the presence of ascites before transplantation (P = 0.03), and the use of LVSS for perihepatic dissection (P < 0.01) were risk factors for developing chylous ascites. According to a multivariate Cox proportional hazards model, the presence of pretransplant ascites [P = 0.04, hazard ratio (HR) = 2.8, 95% confidence interval (CI) = 1.1-13.5] and the use of LVSS for perihepatic dissection (P = 0.01, HR = 5.4, 95% CI = 1.5-34.4) were independent risk factors. In conclusion, the presence of preoperative ascites and the use of LVSS for perihepatic dissection are independent risk factors for the formation of chylous ascites. To our knowledge, this study is the most extensive examination of the development of chylous ascites. Nevertheless, our results should be supported by new prospective trials. Liver Transpl, 2012. (C) 2012 AASLD.en_US
dc.identifier.doi10.1002/lt.23476
dc.identifier.endpage1052en_US
dc.identifier.issn1527-6465
dc.identifier.issue9en_US
dc.identifier.pmid22639428en_US
dc.identifier.scopus2-s2.0-84865602405en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1046en_US
dc.identifier.urihttps://doi.org/10.1002/lt.23476
dc.identifier.urihttps://hdl.handle.net/11616/95789
dc.identifier.volume18en_US
dc.identifier.wosWOS:000307969300007en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofLiver Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTotal Parenteral-Nutritionen_US
dc.subjectVessel Sealing Systemen_US
dc.subjectSomatostatin Analogen_US
dc.subjectLigasureen_US
dc.subjectOctreotideen_US
dc.subjectResolutionen_US
dc.titleChylous ascites after liver transplantation: Incidence and risk factorsen_US
dc.typeArticleen_US

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