Olfactory function, olfactory bulb volume, and quality of life after radiotherapy for nasopharyngeal cancer

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dc.authoridKIZILAY, Ahmet/0000-0003-3048-6489
dc.authorwosidKIZILAY, Ahmet/ABI-8293-2020
dc.contributor.authorKaplan, Bilge Kurnaz
dc.contributor.authorKizilay, Ahmet
dc.contributor.authorKaplan, Fatih
dc.contributor.authorToplu, Yuksel
dc.date.accessioned2024-08-04T20:51:56Z
dc.date.available2024-08-04T20:51:56Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Radiotherapy (RT) is the standard treatment for nasopharyngeal cancer (NPC). Various advers effects may occur after RT. In this study, we aimed to evaluate the advers effects of RT on the olfactory bulb and olfactory function in patients with NPC and describe the impact of these effects on the patients' quality of life. Methods: We investigated 21 patients with NPC who received RT at least 12 months earlier, in addition to 21 age- and sex-matched healthy controls. The participants underwent a detailed nasoendoscopic ear, nose, and throat examination. All participants received orthonasal olfaction tests and a nasopharyngeal magnetic resonance imaging scan to measure olfactory bulb volume; in addition, they filled out a quality of life questionnaire. Results: There was a significant difference between the orthonasal olfactory test results of the patients and controls (p<0.05). The left and right side olfactory bulb volume values of the patients and controls were statistically similar (p=0.07). There was a significant difference between the quality of life questionnaire results of the patients and controls (p<0.05). Conclusion: Olfactory dysfunction was present in the majority of patients with NPC who received RT.en_US
dc.identifier.doi10.5152/B-ENT.2021.21371
dc.identifier.endpage248en_US
dc.identifier.issn1781-782X
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85130156693en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage244en_US
dc.identifier.urihttps://doi.org/10.5152/B-ENT.2021.21371
dc.identifier.urihttps://hdl.handle.net/11616/100654
dc.identifier.volume17en_US
dc.identifier.wosWOS:000738497300007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofB-Enten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOlfactory functionen_US
dc.subjectNasopharyngeal canceren_US
dc.subjectolfactory bulben_US
dc.subjectquality of lifeen_US
dc.subjectradiotherapyen_US
dc.titleOlfactory function, olfactory bulb volume, and quality of life after radiotherapy for nasopharyngeal canceren_US
dc.typeArticleen_US

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