The Changes in Tear Film Parameters and Impression Cytology in Heavily Drinking Men

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dc.authoridGündüz, Abuzer/0000-0003-1752-6810
dc.authoridAKPOLAT, Nusret/0000-0002-9138-2117
dc.authoridKarlıdağ, Rifat/0000-0002-3650-0774
dc.authorwosidGündüz, Abuzer/HLH-2417-2023
dc.authorwosidAKPOLAT, Nusret/ABF-6986-2020
dc.authorwosidkarlıdağ, rıfat/AAB-4255-2021
dc.authorwosidKarlıdağ, Rifat/AAB-4281-2021
dc.contributor.authorCumurcu, Tongabay
dc.contributor.authorGunduz, Abuzer
dc.contributor.authorCumurcu, Birgul Elbozan
dc.contributor.authorGul, Isil Gogcegoz
dc.contributor.authorAkpolat, Nusret
dc.contributor.authorKarlidag, Rifat
dc.date.accessioned2024-08-04T20:37:25Z
dc.date.available2024-08-04T20:37:25Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: To evaluate the tear film function and ocular surface changes in heavily drinking men. Methods: This prospective case-control study involved 35 male subjects with heavy alcohol consumption (group 1) and 35 age-and sex-matched control subjects (group 2). Best-corrected visual acuity measurement, slit-lamp examination, Schirmer I test, tear film break-up time (BUT) measurement, and conjunctival impression cytology were performed in all subjects. The results were compared between the 2 groups. Results: The mean Schirmer I test results in group 1 and group 2 were 8.31 +/- 3.56 mm and 13.17 +/- 5.71 mm, respectively, and the mean BUT values were 9.22 +/- 3.10 seconds and 13.20 +/- 4.04 seconds, respectively. The mean Schirmer I and BUT results were statistically lower in group 1 than in group 2 (P < 0.0001). The mean impression cytology scores in group 1 and group 2 were 2.08 +/- 0.78 and 1.37 +/- 0.94, respectively. A statistically significant difference was noted between the study and control groups for the grading of cytological changes (P = 0.001). Conclusions: Our data showed that heavily drinking men have decreased tear production, tear film instability, and significant degeneration of the ocular surface epithelium when compared with normal subjects.en_US
dc.identifier.doi10.1097/ICO.0b013e31825239d1
dc.identifier.endpage241en_US
dc.identifier.issn0277-3740
dc.identifier.issn1536-4798
dc.identifier.issue3en_US
dc.identifier.pmid22580435en_US
dc.identifier.scopus2-s2.0-84873989581en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage237en_US
dc.identifier.urihttps://doi.org/10.1097/ICO.0b013e31825239d1
dc.identifier.urihttps://hdl.handle.net/11616/95958
dc.identifier.volume32en_US
dc.identifier.wosWOS:000314818700003en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofCorneaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectheavy alcohol consumptionen_US
dc.subjectimpression cytologyen_US
dc.subjectocular surfaceen_US
dc.subjecttear film functionsen_US
dc.titleThe Changes in Tear Film Parameters and Impression Cytology in Heavily Drinking Menen_US
dc.typeArticleen_US

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