An evaluation of inflammation with mean platelet volume in children with celiac disease

dc.contributor.authorAsik, Abdulvahit
dc.contributor.authorDereci, Selim
dc.contributor.authorTekin, Mehmet
dc.date.accessioned2022-03-12T13:29:32Z
dc.date.available2022-03-12T13:29:32Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: The purpose of this study was to evaluate mean platelet volume and platelet distribution width in children with celiac disease.Material and Methods: Fifty children with celiac disease (18 boys, 32 girls) and 63 healthy volunteer children (23 boys, 40 girls) were included in the study. Demographic features such as age, and gender and laboratory values such as platelet count, mean platelet volume, and platelet distribution width were recorded from the patients’ files.Results: Fifty children with celiac disease (18 boys, 32 girls) and 63 healthy volunteer children (23 boys, 40 girls) were included in the study. No statistically significant differences were determined between the celiac disease group and the healthy control group in terms of platelet counts (275,418±70,657/mm3 and 280,888±61,290/mm3, respectively, p=0.661), platelet distribution width (19.27±1.14 fL and 19.16±1.13 fL, respectively, p=0.670) or mean platelet volume (7.31±1.36 fL and 7.38±1.45 fL, respectively, p=0.779). At ROC analysis, a cut off value was determined for platelet distribution width of 18.2 fL with 24.00% sensitivity and 87.30% specificity (AUC: 0.504, 95% Cl: 0.408-0.599 and p=0.947). A cutoff value for mean platelet volume of 0.74 was calculated with 72.00% sensitivity and 44.44% specificity (AUC: 0.520, 95% Cl: 0.424-0.615 and p=0.708).Conclusions: Mean platelet volume values in children with celiac disease were no different to those of the healthy control group. We think that the absence of any change in mean platelet volume, values in children diagnosed with celiac disease may be related to a short duration of inflammation.en_US
dc.identifier.citationAsik, A., Dereci, S., & Tekin, M. (2021). An evaluation of inflammation with mean platelet volume in children with celiac disease . Annals of Medical Researchen_US
dc.identifier.urihttps://hdl.handle.net/11616/55092
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleAn evaluation of inflammation with mean platelet volume in children with celiac diseaseen_US
dc.typeArticleen_US

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