Can red blood cell distribution width (RDW) level predict the severity of acute exacerbation of chronic obstructive pulmonary disease (AECOPD)?

Basit Öğe Kaydı
dc.authoridYalçınsoy, Murat/0000-0003-3407-7359
dc.authoridSoğukpınar, Özlem/0000-0001-8483-8510
dc.authoridGungor, Sinem/0000-0002-1163-125X
dc.authoridtuncay, Eylem Acarturk/0000-0002-5046-1943
dc.authoridGundogus, Baran/0000-0001-9129-5497
dc.authorwosidYalçınsoy, Murat/ABI-1421-2020
dc.authorwosidSoğukpınar, Özlem/IZQ-2191-2023
dc.authorwosidGungor, Sinem/GPX-1807-2022
dc.authorwosidtuncay, Eylem Acarturk/GPX-1832-2022
dc.authorwosidGundogus, Baran/GQH-7792-2022
dc.contributor.authorAlparslan Bekir, Sumeyye
dc.contributor.authorTuncay, Eylem
dc.contributor.authorGungor, Sinem
dc.contributor.authorYalcinsoy, Murat
dc.contributor.authorSogukpinar, Ozlem
dc.contributor.authorGundogus, Baran
dc.contributor.authorAksoy, Emine
dc.date.accessioned2024-08-04T20:50:34Z
dc.date.available2024-08-04T20:50:34Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground Elevated red blood cell distribution width (RDW) levels were associated with mortality in patients with stable chronic obstructive lung pulmonary diseases (COPD). There are limited data about RDW levels in acute exacerbation of COPD (AECOPD). Aim/Objective The association of the RDW levels with the severity of AECOPD was evaluated according to admission location, (outpatient-clinic, ward and intensive care unit (ICU)). Methods Cross sectional retrospective study was designed in tertiary care hospital for chest diseases in 2015. Previously COPD diagnosed patients admitted to hospital outpatient-clinic, ward and ICU due to AECOPD were included in the study. Patients demographics, RDW, biomarkers (CRP, RDW, Neutrophil to lymphocyte ratio (NLR), platelet to mean platelet volume (PLT-MPV)) C-CRP, biochemistry values were recorded from hospital electronic system. RDW values were subdivided below 0.11% (low), above and equal 0.15% (high) and between 0.11%-0.15% (normal). Neutrophil to lymphocyte ratio (NLR) and platelet to mean platelet volume (PLT-MPV) were also calculated. Biomarker values were compared according to where AECOPD was treated. Results 2771 COPD patients (33% female) and 1429 outpatients-clinic, 1156 ward and 186 ICU were enrolled in the study. The median RDW values in outpatients-clinic, ward and ICU were 0.16 (0.09-0.26), 0.07 (0.01-0.14) and 0.01 (0.00-0.07) respectively (P < .001). In outpatient to ward and ICU, low RDW values were significantly increased (31%, 66%, 83%, respectively) and high RDW values significantly decreased (54%, 24%, 10%) (P < .001). According to attack severity, low RDW values were determined. Conclusion Patients with AECOPD, lower RDW values should be considered carefully. Lower RDW can be used for decision of COPD exacerbation severity and follow up treatment responseen_US
dc.identifier.doi10.1111/ijcp.14730
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.issue11en_US
dc.identifier.pmid34383359en_US
dc.identifier.scopus2-s2.0-85113180126en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1111/ijcp.14730
dc.identifier.urihttps://hdl.handle.net/11616/100151
dc.identifier.volume75en_US
dc.identifier.wosWOS:000686421300001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Hindawien_US
dc.relation.ispartofInternational Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectTo-Lymphocyte Ratioen_US
dc.subjectInflammatory Markersen_US
dc.subjectNeutrophilen_US
dc.subjectMortalityen_US
dc.titleCan red blood cell distribution width (RDW) level predict the severity of acute exacerbation of chronic obstructive pulmonary disease (AECOPD)?en_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu