Gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid enhanced magnetic resonance imaging-guided risk assessment in living donor liver transplant patients with postoperative complications: a pilot study

dc.authoridKahraman, Aysegul Sagir/0000-0002-2147-1181
dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authorwosidKahraman, Aysegul Sagir/S-1526-2016
dc.authorwosidYıldırım, İsmail Okan/AFR-8243-2022
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.contributor.authorKolu, M.
dc.contributor.authorKahraman, A. S.
dc.contributor.authorAkbulut, S.
dc.contributor.authorYildirim, I. O.
dc.date.accessioned2024-08-04T20:49:24Z
dc.date.available2024-08-04T20:49:24Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVE: To evaluate whether gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) enhanced magnetic resonance imaging (MRI), the measurements of quantitative and qualitative parameters on hepatobiliary phase images can predict the risk of postoperative complications in patients underwent living donor liver transplantation (LDLT) PATIENTS AND METHODS: We obtained Gd-EOB-DTPA-enhanced 3 Tesla MRI before living donor hepatectomy in donors (donor group: n=30) and after LDLT in their recipients (recipient group; n=30). MRIs were evaluated in terms of quantitative and qualitative variables. Quantitative parameters included relative liver enhancement value, biliary signal intensity value, and muscle signal index value. Qualitative parameters included visual evaluation of the liver and biliary enhancement on hepatobiliary phase images. Patients were followed up for postoperative biliary and vascular complications and divided according to the presence and absence of complications. The relationship between MRI parameters and postoperative complications was statistically analyzed. RESULTS: The mean relative liver enhancement values, mean biliary signal values, and muscle signal index were significantly lower in recipients with postoperative complications than those in donors and recipients without complications (p < 0.001). Visual assessments of liver enhancement and biliary signal were also significantly different in recipients with postoperative complications than that in donors and recipients without complications (p < 0.001). CONCLUSIONS: Quantitative and qualitative MRI parameters obtained by Gd-EOB-DTPA-en- hanced MRI on hepatobiliary phase images may potentially become a reliable tool for the assessment of the risk for postoperative complications after LDLT.en_US
dc.identifier.doi10.26355/eurrev_202103_25211
dc.identifier.endpage2205en_US
dc.identifier.issn1128-3602
dc.identifier.issue5en_US
dc.identifier.pmid33755957en_US
dc.identifier.scopus2-s2.0-85102711532en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2199en_US
dc.identifier.urihttps://doi.org/10.26355/eurrev_202103_25211
dc.identifier.urihttps://hdl.handle.net/11616/99826
dc.identifier.volume25en_US
dc.identifier.wosWOS:000627906600016en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLiving donor liver transplantationen_US
dc.subjectPostoperative complicationsen_US
dc.subjectGadolinium ethoxybenzyl dethylenetrlamine pentaacetic aciden_US
dc.subjectMagnetic resonance imagingen_US
dc.titleGadolinium ethoxybenzyl diethylenetriamine pentaacetic acid enhanced magnetic resonance imaging-guided risk assessment in living donor liver transplant patients with postoperative complications: a pilot studyen_US
dc.typeArticleen_US

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