Evaluation of the effectiveness of anti-IgE treatment in patients with chronic urticaria with an urticarial control test
| dc.contributor.author | Aytekin, Gokhan | |
| dc.contributor.author | Colkesen, Fatih | |
| dc.contributor.author | Arslan, Sevket | |
| dc.contributor.author | Yildiz, Eray | |
| dc.date.accessioned | 2022-03-08T07:37:49Z | |
| dc.date.available | 2022-03-08T07:37:49Z | |
| dc.date.issued | 2019 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Aim: Chronic spontaneous urticaria (CSU) is characterized by recurrent urticaria, angioedema and a combination of both over a period of more than 6 weeks. Anti-immunoglobulin E (IgE) monoclonal antibody (omalizumab) treatment is an effective and safe treatment modality that can be applied in antihistamine-resistant cases in patients with CSU and the urticaria control test is a simple and useful test that evaluates the control level of the disease over the past 4 weeks.Material and Methods: Following appropriate urticaria control tests, 82 test results of 41 patients with CSU (23 females, 18 males) who received subcutaneous anti-IgE treatment at a dose of 300 mg/4 weeks for 6 months were evaluated retrospectively.Results: With each question, there was a statistically significant difference between the mean scores before treatment and at 6 months of treatment (p: 0.001 for question 1, p: 0.001 for question 2, p: 0.001 for question 3, p: 0.001 for question 4). As a result, 95.1% of the patients included in the study achieved a complete and/or partial response to treatment.Conclusion: Omalizumab treatment in patients with chronic spontaneous urticaria (CSU), is an effective and safe treatment modality, independent of the patients’ serum IgE levels, eosinophil counts, thyroid-stimulating hormone levels, C-reactive protein and sedimentation rates, presence or absence of anti-nuclear antibody (ANA) and regardless of whether angioedema is associated with chronic spontaneous urticaria. Furthermore, the urticaria control test is a practical test that can be used to evaluate the efficiency of treatment in CSU patients | en_US |
| dc.identifier.citation | Aytekin, G., Colkesen, F., Yildiz, E., & Arslan, S. (2021). Evaluation of the effectiveness of anti-IgE treatment in patients with chronic urticaria with an urticarial control test . Annals of Medical Research, | en_US |
| dc.identifier.uri | https://hdl.handle.net/11616/54644 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Annals of Medical Research | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | Evaluation of the effectiveness of anti-IgE treatment in patients with chronic urticaria with an urticarial control test | en_US |
| dc.type | Article | en_US |
