CRP/albumin ratio in predicting 1-year mortality in elderly patients undergoing hip fracture surgery
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Verduci Publisher
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
OBJECTIVE: In the literature, rates of up to 37.1% have been reported for 1-year mortality after hip fractures. In this study, we aimed to determine whether the C-reactive protein/albumin ratio (CAR) is an independent risk factor for 1- year mortality after hip fracture and whether CAR, neutrophil/lymphocyte ratio ( NLR), CRP, albumin level, and other parameters have an effect on mortality and morbidity. PATIENTS AND METHODS: Over a 3-year period, 480 patients aged 65 years and older who underwent hemiarthroplasty for hip fracture were analyzed. A univariate logistic regression analysis was performed to identify prognostic factors for 1-year mortality. Significant variables were re- evaluated using binary logistic regression analysis. RESULTS: The number of patients who died within 1 year postoperatively was 95 (27.7%), and the median age was 85 years. In the receiver operating characteristic analysis (ROC) for 1-year mortality after hip fracture, the optimal cut-off value of CAR was found to be 1.03. The area under the curve (AUC) for mortality was 0.843, the sensitivity was 65.3%, and the specificity was 92.7% [95% confidence interval (CI), 0.791-0.895; p < 0.001]. The optimal cut-off value for CRP was 2.85, the AUC was 0.838, the sensitivity was 70%, and the specificity was 89% (95% CI, 0.785- 0.890; p < 0.001). The optimal cutoff value of NLR for postoperative intensive care unit (ICU) admission was determined to be 6.64. CONCLUSIONS: CAR was a predictive factor for 1-year postoperative mortality and postoperative ICU admission, whereas NLR was a predictive factor for postoperative ICU admission.
Açıklama
Anahtar Kelimeler
CRP/albumin ratio, Neutrophil to lymphocyte ratio, Elderly patients, Hip fracture, Mortality
Kaynak
European Review For Medical and Pharmacological Sciences
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
27
Sayı
18
