CRP/albumin ratio in predicting 1-year mortality in elderly patients undergoing hip fracture surgery

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dc.authoridAydin, Ahmet/0000-0003-1836-2061
dc.authorwosidAydin, Ahmet/AAC-4014-2022
dc.contributor.authorAydin, A.
dc.contributor.authorKacmaz, O.
dc.date.accessioned2024-08-04T20:57:34Z
dc.date.available2024-08-04T20:57:34Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVE: In the literature, rates of up to 37.1% have been reported for 1-year mortality after hip fractures. In this study, we aimed to determine whether the C-reactive protein/albumin ratio (CAR) is an independent risk factor for 1- year mortality after hip fracture and whether CAR, neutrophil/lymphocyte ratio ( NLR), CRP, albumin level, and other parameters have an effect on mortality and morbidity. PATIENTS AND METHODS: Over a 3-year period, 480 patients aged 65 years and older who underwent hemiarthroplasty for hip fracture were analyzed. A univariate logistic regression analysis was performed to identify prognostic factors for 1-year mortality. Significant variables were re- evaluated using binary logistic regression analysis. RESULTS: The number of patients who died within 1 year postoperatively was 95 (27.7%), and the median age was 85 years. In the receiver operating characteristic analysis (ROC) for 1-year mortality after hip fracture, the optimal cut-off value of CAR was found to be 1.03. The area under the curve (AUC) for mortality was 0.843, the sensitivity was 65.3%, and the specificity was 92.7% [95% confidence interval (CI), 0.791-0.895; p < 0.001]. The optimal cut-off value for CRP was 2.85, the AUC was 0.838, the sensitivity was 70%, and the specificity was 89% (95% CI, 0.785- 0.890; p < 0.001). The optimal cutoff value of NLR for postoperative intensive care unit (ICU) admission was determined to be 6.64. CONCLUSIONS: CAR was a predictive factor for 1-year postoperative mortality and postoperative ICU admission, whereas NLR was a predictive factor for postoperative ICU admission.en_US
dc.identifier.doi10.26355/eurrev_202309_33770
dc.identifier.endpage8446en_US
dc.identifier.issn1128-3602
dc.identifier.issue18en_US
dc.identifier.pmid37782161en_US
dc.identifier.startpage8438en_US
dc.identifier.urihttps://doi.org/10.26355/eurrev_202309_33770
dc.identifier.urihttps://hdl.handle.net/11616/102728
dc.identifier.volume27en_US
dc.identifier.wosWOS:001097483700015en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCRP/albumin ratioen_US
dc.subjectNeutrophil to lymphocyte ratioen_US
dc.subjectElderly patientsen_US
dc.subjectHip fractureen_US
dc.subjectMortalityen_US
dc.titleCRP/albumin ratio in predicting 1-year mortality in elderly patients undergoing hip fracture surgeryen_US
dc.typeArticleen_US

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