Phytochemical compounds and antiradical, antimicrobial, and cytotoxic activities of the extracts from hypericum scabrum l. Flowers

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dc.contributor.authorKeser, S.
dc.contributor.authorKeser, F.
dc.contributor.authorKaygili, O.
dc.contributor.authorTekin, S.
dc.contributor.authorDemir, E.
dc.contributor.authorTurkoglu, I.
dc.contributor.authorTurkoglu, S.
dc.contributor.authorParlak, A.E.
dc.date.accessioned2019-07-19T06:01:10Z
dc.date.available2019-07-19T06:01:10Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractHypericum scabrum L. has been widely used in traditional medicine for the treatment of many diseases just as the other Hypericum species. In the present study, the antiradical, antimicrobial and cytotoxic activities of water and ethanol extracts of H. scabrum flowers were investigated. Their phytochemical contents and composition were also determined. The water and ethanol extracts are better scavenged ABTS (97.89 and 98.99%) and OH radicals (96.36 and 97.33%); the water extract is better scavenged DPPH radicals (91.66%) than the standard antioxidant BHA (94.33, 85.19, 90.16%, respectively). Flowers of H. scabrum contain flavonoids, phenolic acids, vitamins and phytosterols, dominated by catechin, vanillic acid, vitamin K and ergosterol. The extracts exhibit a strong cytotoxic activity against MCF-7, HCT-116, and LNCaP cancer cell lines. It is found that their antimicrobial activities are higher than the standard antibiotics. These results indicate that H. scabrum flowers have potent antiradical, antimicrobial and cytotoxic activities. © 2018, © 2018 Informa UK Limited, trading as Taylor & Francis Group.en_US
dc.identifier.citationKeser, S. Keser, F. Kaygili, O. Tekin, S.Demir, E. Turkoglu, I. Turkoglu, S. Parlak, A.E. (2018).Phytochemical compounds and antiradical, antimicrobial, and cytotoxic activities of the extracts from hypericum scabrum l. Flowers.en_US
dc.identifier.doi10.1080/14786419.2018.1493735en_US
dc.identifier.endpage0en_US
dc.identifier.issue0en_US
dc.identifier.startpage0en_US
dc.identifier.urihttps://hdl.handle.net/11616/12759
dc.identifier.volume0en_US
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltd.en_US
dc.relation.ispartofNatural Product Researchen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectantimicrobialen_US
dc.subjectantiradicalen_US
dc.subjectcytotoxicen_US
dc.subjectH. scabrumen_US
dc.subjectphytochemicalen_US
dc.titlePhytochemical compounds and antiradical, antimicrobial, and cytotoxic activities of the extracts from hypericum scabrum l. Flowersen_US
dc.typeArticleen_US

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