Fractionated stereotactic radiosurgery for vestibular schwannomas using cyberknife: A single institution experience

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dc.authoridOlmezoglu, Ali/0000-0002-7809-9819;
dc.authorwosidOlmezoglu, Ali/M-7932-2017
dc.authorwosidEkici, Kemal/AFJ-9488-2022
dc.authorwosidEkici, Kemal/AAF-6505-2022
dc.contributor.authorKocak, Mihriban Erdogan
dc.contributor.authorSengul, Adem
dc.contributor.authorEkici, Kemal
dc.contributor.authorOlmezoglu, Ali
dc.contributor.authorSeseogullari, Ozgur
dc.date.accessioned2024-08-04T20:42:34Z
dc.date.available2024-08-04T20:42:34Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To assess tumour control, hearing preservation status, and complication ratio after fractionated stereotactic radiosurgery/radiotherapy by using CyberKnife device in patients with vestibular schwannomas. Methods: This retrospective study was conducted at Izmir Ataturk Research and Tranining Hospital, Turkey, and comprised data of vestibular schwannomas patients treated with stereotactic radiosurgery/radiotherapy from March 2010 to December 2013. The patients were subjected to a dose ranging from 12 to 30Gy using CyberKnife system with an average of three fractions. SPSS 17 was used for data analysis. Paired t-test and Pearson's chi-square test were used to compare clinical parameters between groups. P<0.05 was considered significant. Results: Of the 41 patients, 26(63.4%) were women and 15(36.6%) were men. The median follow-up duration after stereotactic radiosurgery/radiotherapy was 25 months (interquartile range: 9-44 months). Radiographic control evaluation ratio was 95.7% with a median follow- up of 3 years (IQR: 18.5 months). Results of 23(56%) patients showed stabile response, 17(42%) regression response and 1(2%) progression response. There were no statistically significant changes between pre- and post-stereotactic radiosurgery/radiotherapy symptoms (p>0.05). One (2.4%) patient reported new onset facial paresis. Conclusion: Stereotactic radiosurgery/radiotherapy treatment of vestibular schwannomas resulted in a good ratio of tumour control. Hearing preservation status and ratios of toxicity were comparable to published literature.en_US
dc.identifier.endpage1093en_US
dc.identifier.issn0030-9982
dc.identifier.issue9en_US
dc.identifier.pmid27654726en_US
dc.identifier.scopus2-s2.0-84981308700en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage1089en_US
dc.identifier.urihttps://hdl.handle.net/11616/97455
dc.identifier.volume66en_US
dc.identifier.wosWOS:000386138300011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPakistan Medical Assocen_US
dc.relation.ispartofJournal of The Pakistan Medical Associationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectVestibular schwannomaen_US
dc.subjectCyberknifeen_US
dc.subjectStereotactic radiosurgeryen_US
dc.subjectStereotactic radiotherapyen_US
dc.titleFractionated stereotactic radiosurgery for vestibular schwannomas using cyberknife: A single institution experienceen_US
dc.typeArticleen_US

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