Synthesis, characterization and antimicrobial activities of novel silver(I) complexes with coumarin substituted N-heterocyclic carbene ligands

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dc.authoridALICI, Bulent/0000-0001-5009-3223
dc.authoridGünal, Selami/0000-0002-4752-5176
dc.authoridKarataş, Mert Olgun/0000-0001-8500-2088
dc.authorwosidÖzdemir, İlknur/AAA-6216-2021
dc.authorwosidALICI, Bulent/AAG-4203-2019
dc.authorwosidGünal, Selami/AAA-7246-2021
dc.authorwosidKarataş, Mert Olgun/ABG-7848-2020
dc.contributor.authorKaratas, Mert Olgun
dc.contributor.authorOlgundeniz, Begum
dc.contributor.authorGunal, Selami
dc.contributor.authorOzdemir, Ilknur
dc.contributor.authorAlici, Bulent
dc.contributor.authorCetinkaya, Engin
dc.date.accessioned2024-08-04T20:41:28Z
dc.date.available2024-08-04T20:41:28Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractEight new coumarin substituted silver(I) N-heterocyclic carbene (NHC) complexes were synthesized by the interaction of the corresponding imidazolium or benzimidazolium chlorides and Ag2O in dichloromethane at room temperature. Structures of these complexes were established on the basis of elemental analysis, H-1 NMR, C-13 NMR, IR and mass spectroscopic techniques. The antimicrobial activities of carbene precursors and silver NHC complexes were tested against standard strains: Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and the fungi Candida albicans and Candida tropicalis. Results showed that all the compounds inhibited the growth of the all bacteria and fungi strains and some complexes performed good activities against different microorganisms. Among all the compounds, the most lipophilic complex bis[1-(4-methylene-6,8-dimethyl-2H-chromen-2-one)-3-(naphthalene-2-ylmethyl)benzimidazol-2-ylidene]silver(I) dichloro argentate (5e) was found out as the most active one. (c) 2015 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.bmc.2015.12.032
dc.identifier.endpage650en_US
dc.identifier.issn0968-0896
dc.identifier.issn1464-3391
dc.identifier.issue4en_US
dc.identifier.pmid26740157en_US
dc.identifier.scopus2-s2.0-84956807145en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage643en_US
dc.identifier.urihttps://doi.org/10.1016/j.bmc.2015.12.032
dc.identifier.urihttps://hdl.handle.net/11616/97150
dc.identifier.volume24en_US
dc.identifier.wosWOS:000368898500013en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofBioorganic & Medicinal Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntibacterialen_US
dc.subjectAntifungalen_US
dc.subjectCoumarinen_US
dc.subjectCarbeneen_US
dc.subjectSilveren_US
dc.titleSynthesis, characterization and antimicrobial activities of novel silver(I) complexes with coumarin substituted N-heterocyclic carbene ligandsen_US
dc.typeArticleen_US

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