Hepatitis B Before and After Hepatocellular Carcinoma

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dc.authoridHarputluoglu, Muhsin Murat Muhip/0000-0002-9415-147X
dc.authorwosidHarputluoglu, Muhsin Murat Muhip/ABI-3094-2020
dc.contributor.authorHarputluoglu, Murat
dc.contributor.authorCarr, Brian, I
dc.date.accessioned2024-08-04T20:50:51Z
dc.date.available2024-08-04T20:50:51Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractHepatitis B virus (HBV) is the one of most common causes of the hepatocellular carcinoma (HCC), especially in eastern world. The aim of this review is to try to understand the relationship between HBV and HCC and to reveal the role of prevention and treatment of HBV infection in reducing the incidence of HCC. Strategies to prevent HCC due to HBV can be classified into three categories. These are primary, secondary, and tertiary preventions. Hepatitis B vaccine is now in the most vital position in preventing HBV-associated HCC. In patients with chronic hepatitis B infection, suppressing viral load with potent antivirals such as tenofovir disoproxil fumarate (TDF) and entecavir (ETV) prevents the development of HCC and improves prognosis by reducing recurrence after HCC treatments. There is currently no clear consensus on which of these drugs should be preferred. Although data on tenofovir alafenamide (TAF) are scarce, available data with TDF suggest that TAF therapy will also be a strong actor for HCC.en_US
dc.identifier.doi10.1007/s12029-021-00745-4
dc.identifier.endpage1210en_US
dc.identifier.issn1941-6628
dc.identifier.issn1941-6636
dc.identifier.issue4en_US
dc.identifier.pmid34762265en_US
dc.identifier.scopus2-s2.0-85118858374en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1206en_US
dc.identifier.urihttps://doi.org/10.1007/s12029-021-00745-4
dc.identifier.urihttps://hdl.handle.net/11616/100303
dc.identifier.volume52en_US
dc.identifier.wosWOS:000717385700002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Gastrointestinal Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatitis Ben_US
dc.subjectHepatocellular carcinomaen_US
dc.subjectPreventionen_US
dc.titleHepatitis B Before and After Hepatocellular Carcinomaen_US
dc.typeReview Articleen_US

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