Apricot ameliorates alcohol induced testicular damage in rat model

Basit Öğe Kaydı
dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.contributor.authorKurus, Meltem
dc.contributor.authorUgras, Murat
dc.contributor.authorAtes, Burhan
dc.contributor.authorOtlu, Ali
dc.date.accessioned2024-08-04T20:31:18Z
dc.date.available2024-08-04T20:31:18Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, we intended to determine the possible preventive effects of dietary apricot on oxidative stress due to ethanol usage in rat testes. The animals were divided into six groups as follows: Group 1 was control. Group 2 received ethanol. Group 3 were fed with apricot diet for 3 months. Group 4 were fed with apricot diet for 6 months. Group 5 received ethanol and apricot diet for 3 months. Group 6 were fed apricot diet for 3 months, and then ethanol + apricot diet for 3 months. Following sacrification, the testes were treated for morphological (tubular and germ cell histology, Sertoli and Leydig cell counts) and biochemical (superoxide dismutase, glutathion peroxidase, catalase, malondialdehyde) analyses. In Group 2, severe histopathological changes in seminiferous tubules and germ cells were determined as well as tubular degeneration and atrophy. Sertoli and Leydig cell counts in the interstitial tissue were decreased. Biochemical parameters revealed tissue oxidative stress. Similar alterations existed in Group 5, although to a lesser extent. In Groups 1, 3 and 4, no histopathological alterations were noted. Results of Group 6 were similar to the controls. Apricot rich diet may have a preventive role on histopathological changes caused by alcohol in rat testes.(C) 2009 Elsevier Ltd. Ail rights reserved.en_US
dc.description.sponsorshipApricot Research Foundation of Malatya Province; Karapinar Kirlangic Koyleri Tarimsal Kalkinma Kooperatifi Akcadag/Malatya; TURKEYen_US
dc.description.sponsorshipThis study was supported by Apricot Research Foundation of Malatya Province. The apricot used in this study was obtained from Karapinar Kirlangic Koyleri Tarimsal Kalkinma Kooperatifi Akcadag/Malatya/TURKEY.en_US
dc.identifier.doi10.1016/j.fct.2009.07.034
dc.identifier.endpage2672en_US
dc.identifier.issn0278-6915
dc.identifier.issn1873-6351
dc.identifier.issue10en_US
dc.identifier.pmid19651185en_US
dc.identifier.scopus2-s2.0-69549118298en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage2666en_US
dc.identifier.urihttps://doi.org/10.1016/j.fct.2009.07.034
dc.identifier.urihttps://hdl.handle.net/11616/94861
dc.identifier.volume47en_US
dc.identifier.wosWOS:000270527000038en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofFood and Chemical Toxicologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectApricoten_US
dc.subjectAlcoholen_US
dc.subjectTestesen_US
dc.subjectHistopathologyen_US
dc.subjectRaten_US
dc.titleApricot ameliorates alcohol induced testicular damage in rat modelen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu