Portal vein reconstruction with cryopreserved vascular grafts: A two-edged sword

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dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridSaglam, Kutay/0000-0002-0919-8370
dc.authoridKoc, Cemalettin/0000-0002-5676-6772
dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authoridSAHIN, TEVFIK TOLGA/0000-0002-9132-6115
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidSaglam, Kutay/ACN-1173-2022
dc.authorwosidKoc, Cemalettin/B-6430-2018
dc.authorwosidSAHIN, TEVFIK TOLGA/W-2539-2017
dc.contributor.authorSaglam, Kutay
dc.contributor.authorSahin, Tevfik Tolga
dc.contributor.authorUsta, Sertac
dc.contributor.authorKoc, Cemalettin
dc.contributor.authorOtan, Emrah
dc.contributor.authorKayaalp, Cuneyt
dc.contributor.authorAydin, Cemalettin
dc.date.accessioned2024-08-04T20:50:53Z
dc.date.available2024-08-04T20:50:53Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground Portal vein anastomotic complications related to size discrepancy are important causes of morbidity and mortality in pediatric liver transplantation. Interposed vascular grafts in portal vein anastomosis can solve this problem. The aim of this study is to evaluate the results of pediatric liver transplantations performed using cryopreserved interposed vascular grafts between graft portal vein and superior mesenteric vein (SMV)-splenic vein (SpV) confluence. Methods Twenty-nine pediatric patients received liver transplantation using cryopreserved venous grafts in our Liver Transplant Institute between 2013 and 2020 were included in this study. Demographic, clinical, and operative characteristics and postoperative follow-up were analyzed. Results Sixteen patients (55.2%) had portal hypoplasia and five patients (17.2%) had portal vein thrombosis. In total, six patients (20.6%) suffered portal vein thrombosis in the early postoperative period. Three patients (10.3%) experienced portal vein thrombosis in the late postoperative period. Late portal vein thrombosis rate was significantly higher in patients with early portal vein thrombosis (3/6 patients [50%] versus 0/23 patients [0%]; p = .034). Lack of portal flow was significantly higher in patients with both early (50% versus 0%; p = .002) and late portal vein thrombosis (66.7% versus 6.7%; p = .03). Conclusion Preoperative portal vein thrombosis and insufficient flow are important factors affecting success of liver transplant in children. The use of interposed vein grafts in problematic portal anastomoses can overcome portal flow problems.en_US
dc.identifier.doi10.1111/petr.14206
dc.identifier.issn1397-3142
dc.identifier.issn1399-3046
dc.identifier.issue3en_US
dc.identifier.pmid34889009en_US
dc.identifier.scopus2-s2.0-85120775353en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1111/petr.14206
dc.identifier.urihttps://hdl.handle.net/11616/100348
dc.identifier.volume26en_US
dc.identifier.wosWOS:000728415900001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPediatric Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjecthypoplasiaen_US
dc.subjectportal anastomosisen_US
dc.subjectsplenic veinen_US
dc.subjectsuperior mesenteric veinen_US
dc.titlePortal vein reconstruction with cryopreserved vascular grafts: A two-edged sworden_US
dc.typeArticleen_US

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