Malondialdehyde, glutathione and nitric oxide levels in patients with Enterobius vermicularis infection

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dc.authorscopusid23980556000
dc.authorscopusid13611422300
dc.authorscopusid11738942300
dc.authorscopusid6506095368
dc.authorscopusid22979099500
dc.contributor.authorKiran T.R.
dc.contributor.authorKaraman Ü.
dc.contributor.authorÇolak C.
dc.contributor.authorBay Karabulut A.
dc.contributor.authorDaldal N.
dc.date.accessioned2024-08-04T19:59:25Z
dc.date.available2024-08-04T19:59:25Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to investigate the levels of malondialdehyde (MDA) and nitric oxide (NO) which are indicators of oxidative stress and also the level of glutathione (GSH) which is an antioxidant molecule, in patients with Enterobius vermicularis infection. A total of 41 patients (mean age: 36.4 years; 31 were male) and 40 healthy controls (mean age: 40.2 years; 28 were male) were included to the study. None of the patients and controls have had history of hormone/steroid drug use, smoking and alcoholism. The mean level of GSH in patient and control groups were found 1.17 ± 0.02 ?mol/l and 2.49 ± 0.10 ?mol/l; MDA 26.97 ± 2.06 ?mol/l and 19.47 ± 2.25 ?mol/l NO 20.74 ± 0.60 ?mol/dl and 17.83 ± 0.50 ?mol/dl, respectively. The mean GSH level in patient group was statistically significantly lower (p< 0.05) than controls, while the mean MDA and NO levels were statistically significantly higher (p< 0.05). These results indicated that the consumption of GSH was increased due to the severity of oxidative stress in patients infected with E.vermicularis. Detailed experimental and clinical studies are required to enlighten the relation of GSH in the pathogenesis of E.vermicularis infection. Since oxidative stress is increased during enterobiosis, the use of antioxidant agents (e.g. vitamins C and E) for the supportive treatment deserves evaluation.en_US
dc.identifier.endpage167en_US
dc.identifier.issn0374-9096
dc.identifier.issue1en_US
dc.identifier.pmid20455415en_US
dc.identifier.scopus2-s2.0-77749343104en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage165en_US
dc.identifier.urihttps://hdl.handle.net/11616/90622
dc.identifier.volume44en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.relation.ispartofMikrobiyoloji Bultenien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEnterobius vermicularisen_US
dc.subjectGlutathioneen_US
dc.subjectMalondialdehydeen_US
dc.subjectNitric oxideen_US
dc.titleMalondialdehyde, glutathione and nitric oxide levels in patients with Enterobius vermicularis infectionen_US
dc.title.alternativeEnterobius vermicularis i?le enfekte hastalarda malondi?aldehi? d, glutatyon ve ni?tri?k oksi?t düzeyleri?en_US
dc.typeArticleen_US

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