The effects of ephedrine on maternal hypothermia in caesarean sections: a double blind randomized clinical trial

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dc.authoridYologlu, Saim/0000-0002-9619-3462
dc.authoridYücel, Aytaç/0000-0003-0270-8339
dc.authoridErsoy, Mehmet/0000-0002-0724-2825
dc.authoridErdil, Feray Akgül/0000-0002-7544-3717
dc.authoridDurmus, Mahmut/0000-0001-9594-9064
dc.authoridGulhas, Nurcin/0000-0002-2539-9017
dc.authorwosidYologlu, Saim/ABI-8014-2020
dc.authorwosidYücel, Aytaç/ABI-6137-2020
dc.authorwosidDurmuş, Mahmut/AAG-3377-2019
dc.authorwosidErsoy, Mehmet/ACN-2779-2022
dc.authorwosidErdil, Feray Akgül/ABI-2474-2020
dc.authorwosidDurmus, Mahmut/ABH-3006-2020
dc.authorwosidGulhas, Nurcin/A-7281-2018
dc.contributor.authorGulhas, N.
dc.contributor.authorTekdemir, D.
dc.contributor.authorDurmus, M.
dc.contributor.authorYucel, A.
dc.contributor.authorErdil, F. A.
dc.contributor.authorYologlu, S.
dc.contributor.authorErsoy, M. O.
dc.date.accessioned2024-08-04T20:37:51Z
dc.date.available2024-08-04T20:37:51Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBACKGROUND: The purpose of the study was to investigate the effect of bolus and the combination of bolus and infusion of ephedrine on maternal hypotermia which are used for treating maternal hypotension under spinal anaesthesia. PATIENTS AND METHODS: 110 ASA I-II patients who developed maternal hypotension were included into the study. Spinal anaesthesia was performed with 12.5 mg heavy bupivacaine + 15 mu g fentanyl. Group I: Ephedrine bolus 5 mg plus ephedrine infusion, Group B: Ephedrine bolus 5 mg plus normal saline infusion. The systolic blood pressure was allowed to range between 20% from baseline values. Ephedrine solution infusion started after hypotension occurred (0.5 mg/minute). The body temperature under 35.5 degrees C was accepted as hypothermia. The newborns' rectal temperature was measured. Moreover, the Apgar scores, umbilical vein-arterial blood gas and acid-base status were evaluated. RESULTS: In Group I, the body core temperatures which were measured at 9, 18, 33, and 39th minutes were significantly higher than Group B (p < 0.05). The prevalence of maternal hypothermia in Group I was significantly lower than the Group B, which were as 65.5% (36/55) and 85.5% (47/55), respectively (p < 0.05). In Group I, the newborn rectal temperatures and the total dose of ephedrine were significantly higher than Group B (p < 0.05). In Group I, the systolic and mean blood pressures were higher than Group B (p < 0.05). CONCLUSIONS: As a result, we found that combined bolus and infusion of ephedrine for treating maternal hypotension prevents maternal and neonatal hypothermia during caesarean section under spinal anaesthesia compared to bolus administrations alone.en_US
dc.identifier.endpage2058en_US
dc.identifier.issn1128-3602
dc.identifier.issue15en_US
dc.identifier.pmid23884826en_US
dc.identifier.scopus2-s2.0-84884236396en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2051en_US
dc.identifier.urihttps://hdl.handle.net/11616/96207
dc.identifier.volume17en_US
dc.identifier.wosWOS:000325204100009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEphedrineen_US
dc.subjectMaternal hypothermiaen_US
dc.subjectMaternal hypotensionen_US
dc.subjectSpinal anaesthesiaen_US
dc.titleThe effects of ephedrine on maternal hypothermia in caesarean sections: a double blind randomized clinical trialen_US
dc.typeArticleen_US

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