Use of the neutrophil to lymphocyte ratio compare crp for the early prediction of acute pancreatitis severity?
Yükleniyor...
Dosyalar
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: To determine the usefulness of the neutrophil to lymphocyte ratio (NLR) as a diagnostic tool for the early detection and
prediction of acute pancreatitis (AP) severity compared with that of C-reactive protein (CRP).
Material and Methods: The medical records of 464 patients hospitalized with AP between 2006 and 2014 were reviewed. The patients
were classified into two groups: severe AP (SAP) and mild/moderate AP groups. Lymphocyte and neutrophil counts and CRP levels
at the time of admission were noted.
Results: Out of the total number of patients (n = 464), 67 had severe AP. The median NLR was significantly higher in the SAP group
(median of 11.1) than in the mild/moderate AP group (median of 6.9) (p < 0.0001). The sensitivity and specificity of NLR were 83.6%
and 49.4%, respectively, with a cut-off value of 6.8 and an AUC of 0.68. CRP levels were also significantly higher in the SAP group
(median of 189 mg/L) than in the mild/moderate AP group (median of 53.5 mg/L) (p < 0.0001). The sensitivity and specificity of the
CRP values were 83.6 % and 74.9 %, respectively, with a cut-off value of 113 mg/L and an AUC of 0.83.
Conclusion: The NLR was significantly higher in patients with severe AP. However, CRP measurement was superior to NLR as an early
predictor of severe disease.
Açıklama
Anahtar Kelimeler
Kaynak
Annals of Medical Research
WoS Q Değeri
Scopus Q Değeri
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Künye
Erdal Yilmaz, E., Bozdag, Z., Turkoglu, A., Veli Ulger, B., & Arikanoglu, Z. (2021). Use of the neutrophil to lymphocyte ratio compare crp for the early prediction of acute pancreatitis severity? . Annals of Medical Research,
