Medication Persistence in Turkish Children and Adolescents with Attention-Deficit/Hyperactivity Disorder

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dc.authoridErdoğdu, Ayse Burcu/0000-0002-7304-5109
dc.authoridYüksel, Serhat/0000-0002-9858-1266
dc.authorwosidErdoğdu, Ayse Burcu/GZG-5283-2022
dc.authorwosidSoylu, Nusret/AAT-6501-2020
dc.authorwosidYüksel, Serhat/W-1689-2017
dc.contributor.authorAyaz, Muhammed
dc.contributor.authorAyaz, Ayse Burcu
dc.contributor.authorSoylu, Nusret
dc.contributor.authorYuksel, Serhat
dc.date.accessioned2024-08-04T20:39:58Z
dc.date.available2024-08-04T20:39:58Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to investigate medication persistence in Turkish children and adolescents with attention-deficit/hyperactivity disorder (ADHD). The effects of sociodemographic characteristics, symptom severity of ADHD, comorbidity, and treatment-related factors influencing medication persistence in children diagnosed with ADHD were studied. Methods: Medication persistence over a continuous 12 month period was evaluated for 877 children and adolescents between 6 and 18 years of age, who were diagnosed with ADHD for the first time and started to receive medication. Medication persistence was determined according to whether or not taking the prescribed medication continued for 12 months after the initiation of treatment. Whereas the symptom severity of ADHD was assessed by using the Turgay Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV)-based Child and Adolescent Behaviour Disorders Screening and Rating Scale-Parents Form (T-DSM-IV-S), perceived medication efficacy after the first treatment was evaluated by the Clinical Global Impressions-Improvement Scale (CGI-I). Results: In this study, medication persistence over a continuous 12 month period occurred at a rate of 30.2% (n=265) in the subjects studied. The hierarchical regression analysis conducted in this research revealed that younger age, higher hyperactivity/impulsivity symptom severity, use of long-acting methylphenidate, addition of another ADHD medication, addition of other psychotropic medications, absence of side effects, and perceived medication efficacy were associated with successful medication persistence over a continuous 12 month period. Conclusions: Understanding the factors that affect medication persistence in ADHD may improve treatment efficacy and symptom control, while minimizing future risks.en_US
dc.identifier.doi10.1089/cap.2014.0002
dc.identifier.endpage447en_US
dc.identifier.issn1044-5463
dc.identifier.issn1557-8992
dc.identifier.issue8en_US
dc.identifier.pmid25010598en_US
dc.identifier.scopus2-s2.0-84912057781en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage442en_US
dc.identifier.urihttps://doi.org/10.1089/cap.2014.0002
dc.identifier.urihttps://hdl.handle.net/11616/96606
dc.identifier.volume24en_US
dc.identifier.wosWOS:000343286100005en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMary Ann Liebert, Incen_US
dc.relation.ispartofJournal of Child and Adolescent Psychopharmacologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPharmacological-Treatmenten_US
dc.subjectAdhd Medicationen_US
dc.subjectAdherenceen_US
dc.subjectMethylphenidateen_US
dc.subjectStimulantsen_US
dc.subjectPopulationen_US
dc.subjectPatternsen_US
dc.subjectTherapyen_US
dc.subjectAdultsen_US
dc.subjectFamilyen_US
dc.titleMedication Persistence in Turkish Children and Adolescents with Attention-Deficit/Hyperactivity Disorderen_US
dc.typeArticleen_US

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