Determination of free malondialdehyde in human serum by high-performance liquid chromatography

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dc.authoridBaysar, Ahmet/0000-0002-7017-399X
dc.authoridKaratepe, Mustafa/0000-0001-6358-5913;
dc.authorwosidBaysar, Ahmet/Q-1190-2018
dc.authorwosidKaratepe, Mustafa/HII-5655-2022
dc.authorwosidKARATAS, Fikret/W-3340-2018
dc.contributor.authorKaratas, F
dc.contributor.authorKaratepe, M
dc.contributor.authorBaysar, A
dc.date.accessioned2024-08-04T20:13:10Z
dc.date.available2024-08-04T20:13:10Z
dc.date.issued2002
dc.departmentİnönü Üniversitesien_US
dc.description.abstractLipid peroxidation involves the oxidative deterioration of polyunsaturated fatty acids in biomembranes and generates a variety of aldehydic products including malondialdehyde (MDA). To demonstrate the occurrence of lipid peroxidation in biological systems, the production of MDA has been shown to be a relevant indicator. Therefore, we describe a new method for measurement of free malondialdehyde in human serum. A simple, rapid but sensitive method for determination of MDA in human serum was applied to goiter patients and control groups. Patients with goiter had high levels of MDA compared to control groups. Our method is fast and practical for clinical measurements, The detection limit was found to be 1.2 x 10(-8) mol L-1. (C) 2002 Elsevier Science (USA). All rights reserved.en_US
dc.identifier.doi10.1016/S0003-2697(02)00387-1
dc.identifier.endpage79en_US
dc.identifier.issn0003-2697
dc.identifier.issn1096-0309
dc.identifier.issue1en_US
dc.identifier.pmid12441155en_US
dc.identifier.scopus2-s2.0-0036901664en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage76en_US
dc.identifier.urihttps://doi.org/10.1016/S0003-2697(02)00387-1
dc.identifier.urihttps://hdl.handle.net/11616/93453
dc.identifier.volume311en_US
dc.identifier.wosWOS:000179824500010en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAcademic Press Inc Elsevier Scienceen_US
dc.relation.ispartofAnalytical Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHPLCen_US
dc.subjectMDAen_US
dc.subjectserumen_US
dc.subjectgoiteren_US
dc.titleDetermination of free malondialdehyde in human serum by high-performance liquid chromatographyen_US
dc.typeArticleen_US

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