Pregnancy After Liver Transplantation: Risks and Outcomes

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dc.authoridErsan, Veysel/0000-0002-1510-0288
dc.authoridKutluturk, Koray/0000-0002-7030-4953
dc.authoridOzdemir, Fatih/0000-0003-0292-3602
dc.authoridKARAKAS, SERDAR/0000-0001-8314-7806
dc.authoridÖZDEMİR, FATİH/0000-0003-0292-3602
dc.authoridince, volkan/0000-0002-0714-490X
dc.authoridBASKIRAN, ADIL/0000-0002-7536-1631
dc.authorwosidErsan, Veysel/AAB-9595-2020
dc.authorwosidKutluturk, Koray/S-5493-2019
dc.authorwosidözşay, oğuzhan/AAO-1440-2021
dc.authorwosidOzdemir, Fatih/ABH-2875-2020
dc.authorwosidKARAKAS, SERDAR/AAB-3219-2021
dc.authorwosidÖZDEMİR, FATİH/HJI-7585-2023
dc.authorwosidBarut, Bora/ABD-9882-2020
dc.contributor.authorBaskiran, A.
dc.contributor.authorKarakas, S.
dc.contributor.authorInce, V.
dc.contributor.authorKement, M.
dc.contributor.authorOzdemir, F.
dc.contributor.authorOzsay, O.
dc.contributor.authorKutluturk, K.
dc.date.accessioned2024-08-04T20:44:05Z
dc.date.available2024-08-04T20:44:05Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective. The aim of this study was to evaluate the outcomes of liver transplant recipients who became pregnant after transplantation. Methods. The clinical data of all patients who underwent liver transplantation between January 2007 and December 2016 in our liver transplantation institute were reviewed. The following data were analyzed: indications for transplantation, recipient age at the beginning of pregnancy, the interval between transplantation and pregnancy, maternal and fetal complications, type of delivery, the health condition of neonates, and modifications in immunosuppressive therapy. Results. During the study period, 1890 patients underwent liver transplantation. There were 185 women (9.8%) in childbearing age (15-45 years old), and 18 (9.7%) of them became pregnant during the study period. There were a total of 26 pregnancies. The mean age of patients at the time of operation was 25.3 +/- 5.2 years, and the mean interval between operation and conception was 32.7 +/- 15.3 months. Seventeen pregnancies (65.4%) ended in a live birth in the study. Six pregnancies (23%) resulted with no maternal or fetal complications. The most frequent maternal complication during pregnancy was pregnancy induced hypertension (n = 3; 16.6%). Conclusions. Despite advances in immunosuppressive therapy and increasing experience in the management of these patients, pregnancies in liver transplant recipients are still more risky than in the general population for both the mother and the fetus. Thus, the issues related to fertility should be comprehensively discussed with the patients and their partners, preferably before transplantation, and pregnancies in liver transplant recipients should be followed up more carefully by a multidisciplinary team.en_US
dc.identifier.doi10.1016/j.transproceed.2017.04.023
dc.identifier.endpage1878en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue8en_US
dc.identifier.pmid28923640en_US
dc.identifier.scopus2-s2.0-85031721741en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1875en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2017.04.023
dc.identifier.urihttps://hdl.handle.net/11616/97997
dc.identifier.volume49en_US
dc.identifier.wosWOS:000411913900032en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRecipientsen_US
dc.subjectExperienceen_US
dc.titlePregnancy After Liver Transplantation: Risks and Outcomesen_US
dc.typeArticleen_US

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