Evaluation of endothelial function in subclinical hypothyroidism and subclinical hyperthyroidism

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dc.contributor.authorCikim, AS
dc.contributor.authorOflaz, H
dc.contributor.authorOzbey, N
dc.contributor.authorCikim, K
dc.contributor.authorUmman, S
dc.contributor.authorMeric, M
dc.contributor.authorSencer, E
dc.date.accessioned2024-08-04T20:30:44Z
dc.date.available2024-08-04T20:30:44Z
dc.date.issued2004
dc.departmentİnönü Üniversitesien_US
dc.description.abstractSubclinical hypothyroidism and subclinical hyperthyroidism are two frequently occurring conditions for which exact therapeutic approaches have not yet been established. The aim of this study was to compare the endothelial function and carotid artery intimae-media thickness (IMT) of these two groups of patients to euthyroid subjects and to assess the effects of these conditions on endothelial function. Study groups comprised of 25 subclinical hypothyroid patients (mean age, 32.28 +/- 9.67 years), 13 subclinical hyperthyroid patients (mean age, 35.69 +/- 9.67 years), and 23 euthyroid subjects (mean age, 35.87 +/- 7.93 years). They were evaluated for flow-mediated dilatation (FMD), and carotid artery IMT. The groups were matched strictly for atherosclerotic risk factors. The subclinical hypothyroid group was found to have significantly lower FMD values. No significant differences were observed between the groups with respect to other vascular parameters. The only discriminative factor between the groups was the state of their thyroid function. Therefore, subclinical hypothyroidism may have adverse effects on endothelial function independent from other well-known atherosclerotic risk factors.en_US
dc.identifier.doi10.1089/1050725041692891
dc.identifier.endpage609en_US
dc.identifier.issn1050-7256
dc.identifier.issn1557-9077
dc.identifier.issue8en_US
dc.identifier.pmid15320973en_US
dc.identifier.scopus2-s2.0-4143106943en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage605en_US
dc.identifier.urihttps://doi.org/10.1089/1050725041692891
dc.identifier.urihttps://hdl.handle.net/11616/94493
dc.identifier.volume14en_US
dc.identifier.wosWOS:000223486800009en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMary Ann Liebert, Incen_US
dc.relation.ispartofThyroiden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIntima-Media Thicknessen_US
dc.subject20-Year Follow-Upen_US
dc.subjectThyroid-Diseaseen_US
dc.subjectAtherosclerosisen_US
dc.subjectThyrotoxicosisen_US
dc.subjectMechanismsen_US
dc.subjectCommunityen_US
dc.subjectEmbolismen_US
dc.subjectHearten_US
dc.subjectRisken_US
dc.titleEvaluation of endothelial function in subclinical hypothyroidism and subclinical hyperthyroidismen_US
dc.typeArticleen_US

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