Effects of reciprocal interactions between various dietary fats and circadian phases on postprandial hyperlipidemia in rats

dc.authoridKAYHAN, BASAK/0000-0003-3508-2563
dc.authoridSatilmis, Basri/0000-0002-2538-5774
dc.authoridSatilmis, Basri/0000-0002-2538-5774
dc.authorwosidKAYHAN, BASAK/ABH-9314-2020
dc.authorwosidGüldür, Tayfun/AAA-7088-2021
dc.authorwosidSatilmis, Basri/C-5176-2019
dc.authorwosidSatilmis, Basri/JBR-9078-2023
dc.contributor.authorSatilmis, Basri
dc.contributor.authorKayhan, Basak
dc.contributor.authorGuldur, Tayfun
dc.date.accessioned2024-08-04T20:43:11Z
dc.date.available2024-08-04T20:43:11Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractExpression levels of various intestinal proteins involved in postprandial lipoprotein assembly as well as plasma triglyceride concentration exhibit daily oscillations indicating circadian control. The length of the carbon chain and degree and position of unsaturation of fatty acids influence triglyceride secretion by the enterocytes. To this end, effects of reciprocal interactions of various single fats/oil (olive oil, fish oil or butter) gavaging either in active or passive phase were investigated in rats. Fat/oil gavaged in the active phase of circadian rhythm resulted in higher postprandial serum triglyceride levels compared to that in the passive phase. Moreover, olive oil led to higher MTP activity and apo B-48 gene expression, while fish oil gavaging caused more prominent apo B-48 and MTP gene expression when they were given in the passive phase. The present results indicate that circadian time at which fat or oil gavaged once might exert influence on postprandial lipoprotein synthesis/assembly.en_US
dc.description.sponsorshipInonu University Scientific Research Unit [2012/64-149]en_US
dc.description.sponsorshipThis work was supported by the Inonu University Scientific Research Unit [grant number 2012/64-149].en_US
dc.identifier.doi10.1080/09291016.2017.1333199
dc.identifier.endpage91en_US
dc.identifier.issn0929-1016
dc.identifier.issn1744-4179
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85020163166en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage77en_US
dc.identifier.urihttps://doi.org/10.1080/09291016.2017.1333199
dc.identifier.urihttps://hdl.handle.net/11616/97839
dc.identifier.volume49en_US
dc.identifier.wosWOS:000424877300007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiological Rhythm Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCircadian rhythmsen_US
dc.subjectdietary fatsen_US
dc.subjectchylomicronen_US
dc.subjecthyperlipidemiaen_US
dc.subjectmicrosomal triglyceride transfer proteinen_US
dc.titleEffects of reciprocal interactions between various dietary fats and circadian phases on postprandial hyperlipidemia in ratsen_US
dc.typeArticleen_US

Dosyalar