Aliphatic Polyurethane Films Based on Hexamethylene Diisocyanate and Saccharides for Biocompatible Transparent Coating on Optic Medical Devices

dc.authoridBALCIOGLU, Sevgi/0000-0003-0724-4772
dc.authoridGürses, Canbolat/0000-0002-4085-0224
dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authoridKeleştemur, Ünzile/0000-0003-4531-6378
dc.authorwosidBALCIOGLU, Sevgi/O-3576-2015
dc.authorwosidGürses, Canbolat/AAA-6825-2019
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.authorwosidKeleştemur, Ünzile/A-4190-2018
dc.contributor.authorGurses, Canbolat
dc.contributor.authorKaraaslan-Tunc, Merve Goksin
dc.contributor.authorKelestemur, Unzile
dc.contributor.authorBalcioglu, Sevgi
dc.contributor.authorGulgen, Selam
dc.contributor.authorKoytepe, Suleyman
dc.contributor.authorAtes, Burhan
dc.date.accessioned2024-08-04T20:51:37Z
dc.date.available2024-08-04T20:51:37Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPolyurethanes are widely used in daily life, from the textile industry to medical applications. In this study, a biocompatible and transparent coating from polyethylene glycol-based polyurethanes including different type of saccharide (xylose as monosaccharide, sucrose as disaccharide, or starch as polysaccharide) is prepared. Prepared optically transparent polyurethanes are characterized with different instrumental analysis techniques and contact-angle measurements. Thermogravimetric analysis data allow understanding that the synthesized saccharide based polyurethanes are resistant to high temperatures, which means that medical devices can be easily coated with one of the saccharide-based polymers during the manufacturing process. The study results also show that synthesized polyurethane samples having a different kind of saccharides present high biocompatibility and transparency properties via In vitro cytotoxicity analysis and optic transparency tests. For xylose, sucrose, or starch containing polyurethanes, the tranmittance values are 97.72%, 85.20%, and 89.23%, respectively. In addition, scanning electron microscope images show that the samples also have smooth surfaces which can be used for proper coating of medical devices. Consequently, this manuscript addresses synthesis and characterization of the optically transparent polyurethanes based on specific saccharides for biocompatible and transparent surfaces especially in optic medical devices such as colonoscopy applications and laparoscopic detection probes.en_US
dc.description.sponsorshipScientific and Technical Research Council of Turkey (TUBTAK) [111T104]en_US
dc.description.sponsorshipThis study was supported by a grant (111T104) to Burhan ATES from The Scientific and Technical Research Council of Turkey (TUBTAK).en_US
dc.identifier.doi10.1002/star.202100214
dc.identifier.issn0038-9056
dc.identifier.issn1521-379X
dc.identifier.issue3-4en_US
dc.identifier.scopus2-s2.0-85123497180en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1002/star.202100214
dc.identifier.urihttps://hdl.handle.net/11616/100443
dc.identifier.volume74en_US
dc.identifier.wosWOS:000745460700001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofStarch-Starkeen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbiocompatibilityen_US
dc.subjectcoating polyurethaneen_US
dc.subjectstarchen_US
dc.subjectsucroseen_US
dc.subjecttransparenten_US
dc.subjectxyloseen_US
dc.titleAliphatic Polyurethane Films Based on Hexamethylene Diisocyanate and Saccharides for Biocompatible Transparent Coating on Optic Medical Devicesen_US
dc.typeArticleen_US

Dosyalar