Do genetic polymorphisms affect susceptibility to periodontal disease A literature review

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dc.authoriduslu, mustafa özay/0000-0002-9707-1379
dc.authoridToy, Vesile Elif/0000-0001-5183-6295
dc.authorwosiduslu, mustafa özay/S-7657-2019
dc.authorwosidToy, Vesile Elif/ABH-9210-2020
dc.contributor.authorToy, V. E.
dc.contributor.authorUslu, M. O.
dc.date.accessioned2024-08-04T20:45:52Z
dc.date.available2024-08-04T20:45:52Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe pathogenesis of periodontal disease is not solely based on microbial dental plaque but is the result of the multifactorial and complex interaction between infection and host response. Many studies in the literature have demonstrated the differences between individuals in terms of host immune response and the presence of genetic components in numerous pathological conditions. Therefore, periodontitis may be defined as a complex genetic disorder with a phenotype formed by the genetic structure and environmental factors in the affected individual. So, determination of the genetic susceptibility profile associated with periodontitis might be very precious for developing novel diagnostic techniques and individual treatment strategies. To clarify the possible role of genetic polymorphisms in periodontal diseases, we searched PubMed for studies published on the subject since 1997 up to June 2018 and obtained data from original studies, meta analyzes, and systematic reviews. We included only caseucontrol studies with large study populations.en_US
dc.identifier.doi10.4103/njcp.njcp_462_18
dc.identifier.endpage453en_US
dc.identifier.issn1119-3077
dc.identifier.issue4en_US
dc.identifier.pmid30975946en_US
dc.identifier.scopus2-s2.0-85064260469en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage445en_US
dc.identifier.urihttps://doi.org/10.4103/njcp.njcp_462_18
dc.identifier.urihttps://hdl.handle.net/11616/98756
dc.identifier.volume22en_US
dc.identifier.wosWOS:000464368300001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofNigerian Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAggressive periodontitisen_US
dc.subjectchronic periodontitisen_US
dc.subjectgenetic polymorphismsen_US
dc.subjectsusceptibilityen_US
dc.titleDo genetic polymorphisms affect susceptibility to periodontal disease A literature reviewen_US
dc.typeReview Articleen_US

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