Serum levels of apelin, salusin-alpha and salusin-beta in normal pregnancy and preeclampsia

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dc.authoridözer, ali/0000-0002-7144-4915
dc.authoridKaraer, Abdullah/0000-0002-2010-6211
dc.authorwosidözer, ali/ABI-2209-2020
dc.authorwosidSimsek, Yavuz/AAH-9894-2021
dc.authorwosidKaraer, Abdullah/ABI-4667-2020
dc.contributor.authorSimsek, Yavuz
dc.contributor.authorCelik, Onder
dc.contributor.authorYilmaz, Ercan
dc.contributor.authorKaraer, Abdullah
dc.contributor.authorDogan, Cagdas
dc.contributor.authorAydin, Suleyman
dc.contributor.authorOzer, Ali
dc.date.accessioned2024-08-04T20:50:57Z
dc.date.available2024-08-04T20:50:57Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The purpose of this study was to investigate the relationship between the serum apelin, salusin-alpha and salusin-beta levels and preeclampsia. Method: Twenty-one healthy pregnant women (control group) and 48 patients with preeclampsia (study group) were included in the study between August 2010 and February 2011. Serum apelin, salusin-alpha and salusin-beta levels of the groups were compared. Results: The patients in the study group were divided into two categories: mild preeclampsia and severe preeclampsia. The mild preeclampsia group consisted of 31 patients, and the severe preeclampsia group consisted of 17 patients. Serum salusin-alpha and salusin-beta levels of the control and study groups were not significantly different (p > 0.05). Apelin levels were statistically significantly higher in the study group. No statistically significant difference was detected between the mild and severe preeclampsia groups in terms of the mean serum apelin levels. Conclusion: The serum levels of apelin were higher in the pregnant women with preeclampsia; however, there was no positive relationship between serum salusin-alpha and salusin-beta levels and the disease. Larger prospective studies are needed to validate our findings.en_US
dc.identifier.doi10.3109/14767058.2012.660221
dc.identifier.endpage1708en_US
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue9en_US
dc.identifier.pmid22533552en_US
dc.identifier.scopus2-s2.0-85121841237en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1705en_US
dc.identifier.urihttps://doi.org/10.3109/14767058.2012.660221
dc.identifier.urihttps://hdl.handle.net/11616/100383
dc.identifier.volume25en_US
dc.identifier.wosWOS:000307999600034en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal of Maternal-Fetal & Neonatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectApelinen_US
dc.subjecthypertensionen_US
dc.subjectpreeclampsiaen_US
dc.subjectsalusin-alphaen_US
dc.subjectsalusin-betaen_US
dc.titleSerum levels of apelin, salusin-alpha and salusin-beta in normal pregnancy and preeclampsiaen_US
dc.typeArticleen_US

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