Effects of Two Different Techniques of Postoperative Analgesia Management in Liver Transplant Donors: A Prospective, Randomized, Double-Blind Study

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dc.authoridDurmus, Mahmut/0000-0001-9594-9064
dc.authoridaydogan, mustafa said/0000-0002-7106-1156
dc.authorwosidDurmuş, Mahmut/AAG-3377-2019
dc.authorwosidbıçakcıoğlu, murat/ABB-5579-2020
dc.authorwosidDurmus, Mahmut/ABH-3006-2020
dc.authorwosidaydogan, mustafa said/AAA-2828-2021
dc.contributor.authorAydogan, M. S.
dc.contributor.authorBicakcioglu, M.
dc.contributor.authorSayan, H.
dc.contributor.authorDurmus, M.
dc.contributor.authorYilmaz, S.
dc.date.accessioned2024-08-04T20:40:17Z
dc.date.available2024-08-04T20:40:17Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description13th Luso-Brazilian Transplantation Congress / 12th Portuguese Transplantation Congress / 1st Iberian Meeting of Transplantation -- OCT 09-11, 2014 -- Lisbon, PORTUGALen_US
dc.description.abstractThe aim of this study was the compare the donor patients who received intravenous (IV) morphine with patient-controlled analgesia (PCA) or epidural morphine during the early postoperative period who underwent liver transplantation. Forty patients were included in the study and randomly divided into 2 groups in a double-blinded manner. They were given IV morphine 5 mg (Group C), or epidural anesthesia adding morphine (2 mg; Group E) by epidural anesthesia technique starting 15 minutes before the estimated time of completion of surgery. All of the patients received PCA with IV morphine (Group C; PCA device was set to deliver 1 mg morphine with a lockout of 15 minutes and a 4-hour limit of 20 mg, and no continuous infusion) or epidural morphine (Group E; patient-controlled epidural analgesia [PCEA] device was set to deliver 0.5 mg morphine with a lockout of 30 minutes and a 4-hour limit of 10 mg, and no continuous infusion) and were followed up for 24 hours, and pain scores were evaluated by study nurses who were blinded to the study protocol. The visual analogue scale (VAS) scores at rest and at movement and morphine consumption at 12 and 24 hours after operation evaluation time points were significantly higher in Group E than those in Group C (P < .05). Furthermore, total morphine consumption in Group C was significantly higher than that in Group E (P < .05). Epidural morphine via PCEA was associated with decreased postoperative VAS scores and morphine consumption. These findings may be beneficial for managing postoperative analgesia protocols in liver transplant donor patients.en_US
dc.identifier.doi10.1016/j.transproceed.2014.09.184
dc.identifier.endpage1206en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue4en_US
dc.identifier.pmid26036554en_US
dc.identifier.scopus2-s2.0-84930386737en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1204en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2014.09.184
dc.identifier.urihttps://hdl.handle.net/11616/96807
dc.identifier.volume47en_US
dc.identifier.wosWOS:000356184000080en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPain Managementen_US
dc.subjectHepatectomyen_US
dc.subjectMorphineen_US
dc.subjectDonationen_US
dc.subjectImpacten_US
dc.titleEffects of Two Different Techniques of Postoperative Analgesia Management in Liver Transplant Donors: A Prospective, Randomized, Double-Blind Studyen_US
dc.typeConference Objecten_US

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