Severe vitamind D deficiency in chronic renal failure patients on peritoneal dialysis

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dc.authorscopusid6701745769
dc.authorscopusid35432340700
dc.authorscopusid6701497814
dc.authorscopusid55786054100
dc.authorscopusid6701534626
dc.authorscopusid6701726937
dc.authorscopusid6701537701
dc.contributor.authorTaskapan H.
dc.contributor.authorErsoy F.F.
dc.contributor.authorPassadakis P.S.
dc.contributor.authorTam P.
dc.contributor.authorMemmos D.E.
dc.contributor.authorKatopodis K.P.
dc.contributor.authorOzener C.
dc.date.accessioned2024-08-04T19:59:22Z
dc.date.available2024-08-04T19:59:22Z
dc.date.issued2006
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate the prevalence of vitamin D deficiency in chronic renal failure (CRF) patients on peritoneal dialysis (PD) and to correlate the findings with various demographic and renal osteodystrophy markers. Method: This cross-sectional, multicenter study was carried out in 273 PD patients with a mean age of 61.7 ± 10.9 years and mean duration of PD 3.3 ± 2.2 years. It included 123 female and 150 male patients from 20 centers in Greece and Turkey, countries that are on the same latitude, namely, 36 - 42° north. We measured 25(OH)D3 and 1.25(OH)2D3 levels and some other clinical and laboratory indices of bone mineral metabolism. Results: Of these 273 patients 92% (251 patients) had vitamin D deficiency i.e. serum 25(OH)D3 levels less than 15 ng/ml, 119 (43.6%) had severe vitamin D deficiency i.e. serum 25(OH)D3 levels, less than 5 ng/ml, 132 (48.4%) had moderate vitamin D deficiency i.e. serum 25(OH)D3 levels, 5 - 15 ng/ml, 12 (4.4%) vitamin D insufficiency i.e. serum 25(OH)D3 levels 15 - 30 ng/ml and only 10 (3.6%) had adequate vitamin D stores. We found no correlation between 25(OH)D3 levels and PTH, serum albumin, bone alkaline phosphatase, P, and Ca × P. In multiple regression analyses, the independent predictors of 25(OH)D3 were age, presence of diabetes (DM-CRF), levels of serum calcium and serum 1.25(OH)2D3. Conclusion: We found a high prevalence (92%) of vitamin D deficiency in these 273 PD patients, nearly one half of whom had severe vitamin D deficiency. Vitamin D deficiency is more common in DM-CRF patients than in non-DM-CRF patients. Our findings suggest that these patients should be considered for vitamin D supplementation. © 2006 Dustri-Verlag Dr. K. Feistle.en_US
dc.identifier.doi10.5414/cnp66247
dc.identifier.endpage255en_US
dc.identifier.issn0301-0430
dc.identifier.issue4en_US
dc.identifier.pmid17063991en_US
dc.identifier.scopus2-s2.0-33749628838en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage247en_US
dc.identifier.urihttps://doi.org/10.5414/cnp66247
dc.identifier.urihttps://hdl.handle.net/11616/90572
dc.identifier.volume66en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherDustri-Verlag Dr. Karl Feistleen_US
dc.relation.ispartofClinical Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic renal failureen_US
dc.subjectDialysisen_US
dc.subjectSerum 25(OH)Den_US
dc.subjectVitamin D deficiencyen_US
dc.titleSevere vitamind D deficiency in chronic renal failure patients on peritoneal dialysisen_US
dc.typeArticleen_US

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