The CHA2DS2-VASc Risk Score Predicts Total Occlusion in Infarct-Related Arteries in Patients With Non-ST Elevation Myocardial Infarction

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dc.authoridYaşar, Erdoğan/0000-0001-5882-3534
dc.authoridÇakmak, Tolga/0000-0002-4981-5521
dc.authorwosidYaşar, Erdoğan/GOH-1219-2022
dc.authorwosidÇakmak, Tolga/AAN-6803-2021
dc.contributor.authorYasar, Erdogan
dc.contributor.authorBayramoglu, Adil
dc.contributor.authorKarakus, Yasin
dc.contributor.authorCakmak, Tolga
dc.date.accessioned2024-08-04T20:50:25Z
dc.date.available2024-08-04T20:50:25Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractEarly detection of total coronary artery occlusion (TO) in non-ST elevation myocardial infarction (NSTEMI) patients may be beneficial since invasive treatments are initiated more rapidly in appropriate patients. Previous studies have shown that the CHA2DS2-VASc (congestive heart failure, hypertension, age >= 75 years, diabetes mellitus, previous stroke, vascular disease, age between 65 and 74 years, female gender) score is associated with thrombus burden in acute coronary syndromes. We investigated the association between the CHA2DS2-VASc risk score and TO in patients with NSTEMI who underwent coronary angiography. TIMI (thrombolysis in myocardial infarction) flow 0 was defined as TO and TIMI flow 1-3 was defined as non-total occlusion (non-TO). The NSTEMI patients (n = 400) included were separated into two groups: those with (n = 138) and without (n = 262) TO. We observed that the CHA2DS2-VASc score was higher in the TO group (3.86 +/- 2.32 vs 2.15 +/- 1.79, P <.001). The Global Registry of Acute Coronary Events (GRACE) score (P = .002) and the CHA2DS2-VASc score (P < .001) were also found to be significant independent predictors for total occlusion in multiple regression analysis. A CHA2DS2-VASc score >= 3 had 68.1% sensitivity and 64.0% specificity (area under the curve (AUC): 0.657, 95% CI: 0.585-0.725, P < .001) for predicting TO. The CHA2DS2-VASc score was an effective tool that predicted TO in patients with NSTEMI.en_US
dc.identifier.doi10.1177/00033197211031324
dc.identifier.endpage386en_US
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue4en_US
dc.identifier.pmid34275378en_US
dc.identifier.scopus2-s2.0-85110851256en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage380en_US
dc.identifier.urihttps://doi.org/10.1177/00033197211031324
dc.identifier.urihttps://hdl.handle.net/11616/100057
dc.identifier.volume73en_US
dc.identifier.wosWOS:000676884200001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofAngiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectacute myocardial infarctionen_US
dc.subjectCHA2DS2-VASc scoreen_US
dc.subjectcoronary angiographyen_US
dc.titleThe CHA2DS2-VASc Risk Score Predicts Total Occlusion in Infarct-Related Arteries in Patients With Non-ST Elevation Myocardial Infarctionen_US
dc.typeArticleen_US

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