Serum levels of apelin, salusin-alpha and salusin-beta in normal pregnancy and preeclampsia

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dc.authorscopusid6603256061
dc.authorscopusid7004349870
dc.authorscopusid55274353300
dc.authorscopusid15044572800
dc.authorscopusid55185500500
dc.authorscopusid7005387041
dc.authorscopusid35520086500
dc.contributor.authorSimsek Y.
dc.contributor.authorCelik O.
dc.contributor.authorYilmaz E.
dc.contributor.authorKaraer A.
dc.contributor.authorDogan C.
dc.contributor.authorAydin S.
dc.contributor.authorOzer A.
dc.date.accessioned2024-08-04T20:02:26Z
dc.date.available2024-08-04T20:02:26Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The purpose of this study was to investigate the relationship between the serum apelin, salusin-alpha and salusin-beta levels and preeclampsia. Method: Twenty-one healthy pregnant women (control group) and 48 patients with preeclampsia (study group) were included in the study between August 2010 and February 2011. Serum apelin, salusin-alpha and salusin-beta levels of the groups were compared. Results: The patients in the study group were divided into two categories: mild preeclampsia and severe preeclampsia. The mild preeclampsia group consisted of 31 patients, and the severe preeclampsia group consisted of 17 patients. Serum salusin-alpha and salusin-beta levels of the control and study groups were not significantly different (p > 0.05). Apelin levels were statistically significantly higher in the study group. No statistically significant difference was detected between the mild and severe preeclampsia groups in terms of the mean serum apelin levels. Conclusion: The serum levels of apelin were higher in the pregnant women with preeclampsia; however, there was no positive relationship between serum salusin-alpha and salusin-beta levels and the disease. Larger prospective studies are needed to validate our findings. © 2012 Informa UK, Ltd.en_US
dc.identifier.doi10.3109/14767058.2011.660221
dc.identifier.endpage1708en_US
dc.identifier.issn1476-7058
dc.identifier.issue9en_US
dc.identifier.pmid22533552en_US
dc.identifier.scopus2-s2.0-84860190760en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1705en_US
dc.identifier.urihttps://doi.org/10.3109/14767058.2011.660221
dc.identifier.urihttps://hdl.handle.net/11616/91686
dc.identifier.volume25en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Maternal-Fetal and Neonatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectApelinen_US
dc.subjectHypertensionen_US
dc.subjectPreeclampsiaen_US
dc.subjectSalusin-alphaen_US
dc.subjectSalusin-betaen_US
dc.titleSerum levels of apelin, salusin-alpha and salusin-beta in normal pregnancy and preeclampsiaen_US
dc.typeArticleen_US

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