Consequences of the Use of Extended Criteria Donors in Living Donor Liver Transplantation

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dc.authoridIsik, Burak/0000-0002-2395-3985
dc.authoridErsan, Veysel/0000-0002-1510-0288
dc.authoridAtes, Mustafa/0000-0003-2821-453X
dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authorwosidIsik, Burak/A-6657-2018
dc.authorwosidErsan, Veysel/AAB-9595-2020
dc.authorwosidAtes, Mustafa/ABI-5100-2020
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.contributor.authorDirican, Abuzer
dc.contributor.authorOzsoy, Mustafa
dc.contributor.authorAtes, Mustafa
dc.contributor.authorErsan, Veysel
dc.contributor.authorGonultas, Fatih
dc.contributor.authorIsik, Burak
dc.contributor.authorYilmaz, Sezai
dc.date.accessioned2024-08-04T20:40:10Z
dc.date.available2024-08-04T20:40:10Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Donor selection criteria are being continuously modified to expand the potential donor pool in living donor liver transplantation (LDLT). This retrospective study reports our center's experience in utilizing extended criteria donors for LDLT. Material/Methods: The charts of 342 LDLT donors who underwent right hepatectomy between September 2007 and December 2010 were reviewed. Donors who were older than 55 years, and/or with BMI >30, and/or with a remnant liver volume of <30% were defined as extended criteria donors. The surgical complications in the extended criteria donors and non-extended criteria donors were compared. Results: There were 61 extended criteria donors (21 male, 40 female; mean age 41 years) and 281 non-extended criteria donors (189 male, 92 female; mean age 31 Years). Surgical morbidities were observed in 70 (20.4%) of donors. The number of patients with complications according to Clavien's system were: Grade I, 30 (43%); Grade II, 11 (16%); Grade IIIa, 12 (17%); Grade IIIb, 16 (23%); and Grade IV, 1 (1%). Postoperative complications were observed in 17 (28%) of 61 extended criteria donors, and 53 (19%) of 281 non-extended donors (p>0.05). However, only the Grade IIIb complication rate in donors with extended criteria was significantly higher than in non-extended criteria donors (p=0.04). Complications developed in 3 of 7 donors aged >55 years and with BMI >30. There was no donor mortality. Conclusions: Although there was no statistical difference between the 2 groups' postoperative complication rates, Grade IIIb complications were statistically significantly higher in the extended group. Having more than 1 extended criteria may increase the donor's postoperative complications in LDLT. Thus, the elimination of the donors should be considered in the presence of more than 1 extended criteria.en_US
dc.identifier.endpage217en_US
dc.identifier.issn1425-9524
dc.identifier.pmid25877045en_US
dc.identifier.scopus2-s2.0-84928012457en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage211en_US
dc.identifier.urihttps://hdl.handle.net/11616/96755
dc.identifier.volume20en_US
dc.identifier.wosWOS:000353301400001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInt Scientific Literature, Incen_US
dc.relation.ispartofAnnals of Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDonor Selectionen_US
dc.subjectLiver Transplantationen_US
dc.subjectLiving Donorsen_US
dc.subjectMorbidityen_US
dc.titleConsequences of the Use of Extended Criteria Donors in Living Donor Liver Transplantationen_US
dc.typeArticleen_US

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