Evaluation of repolarization dispersion in patients with idiopathic pulmonary fibrosis

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dc.contributor.authorEyyüpkoca, Ferhat
dc.contributor.authorHidayet, Siho
dc.contributor.authorAltıntaş, Mehmet Sait
dc.contributor.authorYüksel, Yasin
dc.contributor.authorDemirkol, Barış
dc.contributor.authorÇetinkaya, Erdoğan
dc.date.accessioned2024-08-04T19:53:18Z
dc.date.available2024-08-04T19:53:18Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIdiopathic pulmonary fibrosis (IPF) is a serious lung disease of unknown etiology and characterized by interstitial fibrosis. The patients usually present with potentially fatal cardiac arrhythmias. This study aimed to investigate indicators of arrhythmia based on electrocardiography (ECG) in patients with IPF. ECG indicators of ventricular depolarization (VD) and repolarization (VR) (QT, QTc, QTd, QTdc, Tp-e, JT and JTc intervals, Tp-e / QT ratio, Tp-e / QTc ratio, Tp-e / JT ratio, and Tp-e / JTc ratio) were analyzed retrospectively in patients with IPF (n:52) and compared with the healthy control group (n:52). The mean QRS interval was lower in patients with IPF compared to the control group, indicators of VD and VR were higher in patients with IPF compared to the control group (p < 0.05). A positive correlation was found between indicators of VD and VR and inflammation markers (CRP and cTn-I) (p < 0.05). We found that indicators of VD and VR were higher in patients with IPF and that is positively correlated with inflammatory markers. Inflammation in cases of IPF may be associated with the development of malignant or chronic cardiac arrhythmias.en_US
dc.identifier.doi10.5455/medscience.2021.11.381
dc.identifier.endpage681en_US
dc.identifier.issn2147-0634
dc.identifier.issue2en_US
dc.identifier.startpage677en_US
dc.identifier.trdizinid1120224en_US
dc.identifier.urihttps://doi.org/10.5455/medscience.2021.11.381
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1120224
dc.identifier.urihttps://hdl.handle.net/11616/89671
dc.identifier.volume11en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isotren_US
dc.relation.ispartofMedicine Scienceen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of repolarization dispersion in patients with idiopathic pulmonary fibrosisen_US
dc.typeArticleen_US

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