Histopathological Features of Gallbladder Specimens Obtained From Liver Recipients

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dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authoridGARZALI, IBRAHIM UMAR/0000-0002-9797-851X
dc.authoridSARICI, KEMAL BARIŞ/0000-0001-9595-1906
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.authorwosidGARZALI, IBRAHIM UMAR/ITU-1475-2023
dc.authorwosidSARICI, KEMAL BARIŞ/ABI-4356-2020
dc.contributor.authorSarici, Kemal Baris
dc.contributor.authorAkbulut, Sami
dc.contributor.authorKarabulut, Ertugrul
dc.contributor.authorSahin, Tevfik Tolga
dc.contributor.authorKucukakcali, Zeynep
dc.contributor.authorGarzali, Ibrahim Umar
dc.contributor.authorAloun, Ali
dc.date.accessioned2024-08-04T20:53:21Z
dc.date.available2024-08-04T20:53:21Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground. To evaluate the histopathological features of gallbladder specimens obtained from liver transplantation (LT) recipients and to find the correlation between these findings with the clinical features of patients. Methods. The 1985 patients who underwent LT in our institute between March 2002 and January 2021 and whose data regarding pathologic analysis of gallbladder could retrospectively be obtained were included in the study. The data of the patients including age, gender, the reason for LT (fulminant or nonfulminant), presence of ascites, macroscopic characteristics of gallblad-der (the length, diameter, and wall thickness), and microscopic findings were all obtained and analyzed in the present study. Results. A total of 1985 patients (men = 1300 and women = 685) with a median age of 39.4 years were included in this study. LT was performed in 249 patients because of fulminant liver failure, and abdominal ascites were detected in 933 patients during LT. There were statisti-cal differences in terms of age (P < .001), gallbladder length (P < .001). and width (P < .001) among the both gender, but there was no difference in terms of histopathologic characteristics and presence of gallstones. On the other hand, there were significant differences in terms of age (P < .001), gallbladder length (P < .001), width (P < .001), wall thickness (P = .021), presence of gallstones (P < .001), and histopathologic characteristics (P < .001) between the patients with fulminant and nonfulminant liver failure etiologies. Similar results were obtained when characteristics of patients with and without ascites were compared. Conclusions. This the first study analyzing the histopathological analysis of gallbladder specimens in LT recipients. Chronic liver disease, presence of ascites and gender are the factors affecting the macroscopic and microscopic features of the gallbladder.en_US
dc.identifier.doi10.1016/j.transproceed.2022.11.011
dc.identifier.endpage1277en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue5en_US
dc.identifier.pmid36604252en_US
dc.identifier.scopus2-s2.0-85146036954en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1273en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2022.11.011
dc.identifier.urihttps://hdl.handle.net/11616/101107
dc.identifier.volume55en_US
dc.identifier.wosWOS:001035850700001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCirrhosisen_US
dc.subjectGallstonesen_US
dc.titleHistopathological Features of Gallbladder Specimens Obtained From Liver Recipientsen_US
dc.typeArticleen_US

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