IS THERE A RELATIONSHIP BETWEEN SERUM IGF-1 AND THYROID NODULE, THYROID OR OVARIAN VOLUME IN POLYCYSTIC OVARIAN SYNDROME?

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dc.contributor.authorTopaloglu, O.
dc.contributor.authorEvren, B.
dc.contributor.authorUzun, M.
dc.contributor.authorYologlu, S.
dc.contributor.authorGuldogan, E.
dc.contributor.authorSahin, I
dc.date.accessioned2024-08-04T20:50:36Z
dc.date.available2024-08-04T20:50:36Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractContext. Studies investigating the association between serum IGF-1, and thyroid nodule, ovarian or thyroid volume in polycystic ovarian syndrome (PCOS) are limited. Objective. We aimed to analyze the association between serum IGF-1 level, and ovarian or thyroid volume, or thyroid nodule in PCOS. Design. The study was performed between June 2017 and August 2019 as prospective design. Subjects and Methods. Adult females with new-onset PCOS were included. The patients having comorbid illness, or using medication were excluded. Basic tests, thyroid and ovarian sonography were performed. The patients were grouped according to thyroid nodule(absent/present) and ovarian volume (<10mL/>= 10mL). We planned to find a positive association between IGF-1, and thyroid nodule, thyroid or ovarian volume in PCOS. Results. Of total 118 patients, 11(9%) had thyroid nodule. The patients with thyroid nodule had a higher ovarian volume (p=0.006). No correlation was found between GH or IGF-1, and thyroid or ovarian volume. IGF-1 was not a predictor for thyroid nodule or higher ovarian volume. Thyroid nodule was a significant predictor for higher ovarian volume. Conclusion. Our study is the first to analyze the association between IGF-1 and thyroid nodule in PCOS. We found that thyroid nodule was associated with thyroid and ovarian volume, but IGF-1 was not associated with thyroid nodule, thyroid or ovarian volume.en_US
dc.identifier.doi10.4183/aeb.2021.138
dc.identifier.endpage146en_US
dc.identifier.issn1841-0987
dc.identifier.issn1843-066X
dc.identifier.issue1en_US
dc.identifier.pmid34539923en_US
dc.identifier.scopus2-s2.0-85113895750en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage138en_US
dc.identifier.urihttps://doi.org/10.4183/aeb.2021.138
dc.identifier.urihttps://hdl.handle.net/11616/100173
dc.identifier.volume17en_US
dc.identifier.wosWOS:000691395500020en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEditura Acad Romaneen_US
dc.relation.ispartofActa Endocrinologica-Bucharesten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectpolycystic ovarian syndromeen_US
dc.subjectIGF 1en_US
dc.subjectthyroid noduleen_US
dc.subjectPCOSen_US
dc.subjectovarian volumeen_US
dc.subjectthyroid volumeen_US
dc.titleIS THERE A RELATIONSHIP BETWEEN SERUM IGF-1 AND THYROID NODULE, THYROID OR OVARIAN VOLUME IN POLYCYSTIC OVARIAN SYNDROME?en_US
dc.typeArticleen_US

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