The Association of Gene Polymorphisms Linked to Caffeine Use with Athletic Performance

Basit Öğe Kaydı
dc.authoridNobari, Hadi/0000-0001-7951-8977
dc.authoridEken, Özgür/0000-0002-5488-3158
dc.authorwosidNobari, Hadi/AAO-9721-2021
dc.authorwosidEken, Özgür/ABE-8274-2020
dc.contributor.authorYildirim, Selin
dc.contributor.authorBulgay, Celal
dc.contributor.authorErgun, Mehmet Ali
dc.contributor.authorEken, Ozgur
dc.contributor.authorCeylan, Halil Ibrahim
dc.contributor.authorNobari, Hadi
dc.contributor.authorCerit, Mesut
dc.date.accessioned2024-08-04T20:54:46Z
dc.date.available2024-08-04T20:54:46Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractCaffeine's use as a performance-enhancing supplement among professional athletes progressively increased after it was taken off the World Anti-Doping Agency's (WADA) list of banned substances. The present review looks at the interactions caused by different levels of caffeine ergogenicity in athletes and gene polymorphisms that affect caffeine ergogenic effect in the current literature. Therefore, a comprehensive analysis of the studies available in the literature and the respective study results have evaluated caffeine ergogenicity in athletes and gene polymorphisms. The search for studies was performed through five databases. Individual responses to caffeine consumption may differ from person to person due to multigene and multifactorial interactions. Adenosine A2A receptor (ADORA2A) and Cytochrome P450 1A2 (CYP1A2) are two genes thought to have the most effects on caffeine's ergogenicity. The function of these two genes accounts for most inter-individual variations in studies after caffeine ingestion. Based on the findings, it is understood that the contribution of caffeine use to individual performance development varies over time due to changes in both environmental and epigenetic interactions, as well as parameters such as circadian rhythm, training loads, nutritional routine, habitual caffeine use, drug intake, expectation, time of consumption, and heredity. As a result, individual caffeine responses are highly complex and involve multiple modifiers.en_US
dc.identifier.doi10.12996/gmj.2023.95
dc.identifier.endpage483en_US
dc.identifier.issn2147-2092
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85173979345en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage478en_US
dc.identifier.urihttps://doi.org/10.12996/gmj.2023.95
dc.identifier.urihttps://hdl.handle.net/11616/101622
dc.identifier.volume34en_US
dc.identifier.wosWOS:001094769100020en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGazi Univ, Fac Meden_US
dc.relation.ispartofGazi Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCaffeineen_US
dc.subjectathleteen_US
dc.subjectexerciseen_US
dc.subjectathletic performanceen_US
dc.subjectCYP1A2en_US
dc.subjectADORA2Aen_US
dc.titleThe Association of Gene Polymorphisms Linked to Caffeine Use with Athletic Performanceen_US
dc.typeReview Articleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu