α-Galactosidase levels in irritable bowel syndrome subtypes and quality of life of patients
| dc.contributor.author | Soysal, Tuba | |
| dc.contributor.author | Ermis, Fatih | |
| dc.contributor.author | Ankarali, Handan | |
| dc.date.accessioned | 2022-03-15T08:49:48Z | |
| dc.date.available | 2022-03-15T08:49:48Z | |
| dc.date.issued | 2021 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Aim: There is a requirement for a reliable serologic marker that can be used for the diagnosis of Irritable Bowel Syndrome (IBS). The aim of our study was to research whether serum levels of Alpha-galactosidase (AG) is associated with IBS and to assess quality of life (QOL) of IBS patients. Materials and Methods: 110 adult patients who were diagnosed with IBS were evaluated. 90 patients and 25 healthy volunteers were included. Patients were classified into subtypes: IBS-Diarrhea (IBS-D), IBS-Constipation (IBS-C), IBS-Mixed (IBS-M), and 30 patients were enrolled for each group. We administered the Short Form 36 (SF-36) to participants to evaluate QOL. Serum AG levels of participants was determined. Results: The mean AG levels of IBS-C and control group were significantly lower than the other groups (p<0.05). The SF-36 questionnaire scores, except for the vitality and mental health domains, were higher significantly in the control group compared to IBS patients (p<0.05). The mean scores of IBS subtypes were similar. In addition, the mean physical functioning score of the control group was higher in comparison with the IBS-D group significantly (p<0.05). Conclusion: Our study has shown that IBS impairs QOL in patients. In addition, we suggest that future studies needed for the role of AG deficiency in IBS patients. | en_US |
| dc.identifier.citation | Soysal, T., Ermis, F., & Ankarali, H. (2021). α-Galactosidase levels in irritable bowel syndrome subtypes and quality of life of patients. Annals of Medical Research | en_US |
| dc.identifier.uri | https://hdl.handle.net/11616/55590 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Annals of Medical Research | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | α-Galactosidase levels in irritable bowel syndrome subtypes and quality of life of patients | en_US |
| dc.type | Article | en_US |
