Living donor liver transplantation for Echinococcus Alveolaris: single-center experience

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dc.authoridOzdemir, Fatih/0000-0003-0292-3602
dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridince, volkan/0000-0002-0714-490X
dc.authoridÖZDEMİR, FATİH/0000-0003-0292-3602
dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authorwosidOzdemir, Fatih/ABH-2875-2020
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidBarut, Bora/ABD-9882-2020
dc.authorwosidKayaalp, Cuneyt/AAH-1764-2021
dc.authorwosidince, volkan/M-7325-2017
dc.authorwosidÖZDEMİR, FATİH/HJI-7585-2023
dc.contributor.authorOzdemir, Fatih
dc.contributor.authorInce, Volkan
dc.contributor.authorBarut, Bora
dc.contributor.authorOnur, Asim
dc.contributor.authorKayaalp, Cuneyt
dc.contributor.authorYilmaz, Sezai
dc.date.accessioned2024-08-04T20:40:22Z
dc.date.available2024-08-04T20:40:22Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractEchinococcus alveolaris (EA) causes a hepatic zoonotic infection and behaves like a malignant tumor during invasion. Liver transplantation (LT) is the only curative treatment option for this unresectable disease. Here, we share our experience with living donor liver transplantation (LDLT) due to EA from the time between March 2002 and November 2014 at the Liver Transplantation Institute of nonu University. Ten patients (mean age, 38.6 years) undergoing LDLT because of unresectable EA were evaluated preoperatively, and the operative and follow-up data were analyzed retrospectively. The mean time interval between diagnosis and LT was 27 months. The mean operation time and mean intraoperative blood requirement were 613 minutes and 4 units of packed red blood cells, respectively. Diaphragmatic resections were performed in 3 patients, and vena cava replacement was performed in 2 patients because of difficulties in removing the extended disease. The local recurrence and distant metastasis rates were 10% and 20%, respectively. The mean survival time was 19.5 months (range, 0-54 months), and the mortality rate was 30%. Unresectable hepatic alveolar echinococcosis is a rare indication for LT and presents some technical difficulties during surgery because diaphragmatic resection, vascular reconstruction, or multiple blood transfusions may be needed. LDLT can be performed successfully in patients with this rare infectious disease, with careful follow-up for potential recurrence and metastasis and administration of low-dose immunosuppressive agents. Liver Transpl 21:1091-1095, 2015. (c) 2015 AASLD.en_US
dc.identifier.doi10.1002/lt.24170
dc.identifier.endpage1095en_US
dc.identifier.issn1527-6465
dc.identifier.issn1527-6473
dc.identifier.issue8en_US
dc.identifier.pmid25981332en_US
dc.identifier.scopus2-s2.0-84937973037en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1091en_US
dc.identifier.urihttps://doi.org/10.1002/lt.24170
dc.identifier.urihttps://hdl.handle.net/11616/96880
dc.identifier.volume21en_US
dc.identifier.wosWOS:000358689500012en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofLiver Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiseaseen_US
dc.titleLiving donor liver transplantation for Echinococcus Alveolaris: single-center experienceen_US
dc.typeArticleen_US

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