The effect of varicocoelectomy on the relationship of oxidative stress in peripheral and internal spermatic vein with semen parameters

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dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X
dc.authoridTANBEK, Kevser/0000-0003-2099-2273
dc.authoridCaner, Ediz/0000-0001-9717-1209
dc.authoridCrozier, Alan/0000-0001-7581-6782
dc.authoridCAMTOSUN, Ahmet/0000-0002-5390-9088
dc.authoridTanbek, Kevser/0000-0003-2099-2273
dc.authoridAlan, Cabir/0000-0002-6024-4475
dc.authorwosidÇOLAK, CEMİL/ABI-3261-2020
dc.authorwosidTANBEK, Kevser/ITR-9264-2023
dc.authorwosidCaner, Ediz/H-9473-2018
dc.authorwosidCrozier, Alan/H-6642-2017
dc.authorwosidCAMTOSUN, Ahmet/ABI-8300-2020
dc.authorwosidTekin, Suat/IZD-9868-2023
dc.authorwosidTekin, Suat/AAG-1440-2021
dc.contributor.authorAltintas, R.
dc.contributor.authorEdiz, C.
dc.contributor.authorCelik, H.
dc.contributor.authorCamtosun, A.
dc.contributor.authorTasdemir, C.
dc.contributor.authorTanbek, K.
dc.contributor.authorTekin, S.
dc.date.accessioned2024-08-04T20:41:36Z
dc.date.available2024-08-04T20:41:36Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this prospective controlled study was to investigate the levels of reactive oxygen species (ROS), including asymmetric dimethylarginine (ADMA), oxidative stress index (OSI) and total oxidant capacity (TOC), and antioxidants with total antioxidant capacity (TAC) in peripheral and internal spermatic veins blood, the relationship of these factors with sperm parameters in the infertile varicocoele patients, and the amelioration effect of varicocoelectomy on these outcomes. Thirty-one primary infertile varicocoele patients and 31 fertile control patients evaluated for determining the levels of ADMA, TOC, OSI, superoxide dismutase (SOD), glutathione (GSH), TAC, and semen analysis. The patients' preoperative SOD, GSH and TAC levels, which were significantly lower than the controls, significantly increased postoperatively. Although SOD and GSH were significantly higher in spermatic vein compared to median cubital vein, TAC was significantly higher in median cubital vein. ADMA, TOC and OSI were significantly higher in the patient group. TOC and OSI were significantly higher in spermatic vein compared to median cubital vein. Postoperative TOC, OSI and ADMA reduced to the control levels. Total antioxidant capacity in the peripheral circulation and oxidative stress index in the internal spermatic vein could give an idea about the possible improvement in sperm count acquired by varicocoelectomy.en_US
dc.identifier.doi10.1111/andr.12172
dc.identifier.endpage446en_US
dc.identifier.issn2047-2919
dc.identifier.issn2047-2927
dc.identifier.issue3en_US
dc.identifier.pmid26945912en_US
dc.identifier.scopus2-s2.0-84959572911en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage442en_US
dc.identifier.urihttps://doi.org/10.1111/andr.12172
dc.identifier.urihttps://hdl.handle.net/11616/97208
dc.identifier.volume4en_US
dc.identifier.wosWOS:000375881200011en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAndrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectasymmetric dimethylarginineen_US
dc.subjectoxidative stress indexen_US
dc.subjecttotal antioxidant capacityen_US
dc.subjecttotal oxidant capacityen_US
dc.subjectvaricocoeleen_US
dc.titleThe effect of varicocoelectomy on the relationship of oxidative stress in peripheral and internal spermatic vein with semen parametersen_US
dc.typeArticleen_US

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