Assessment of Atrial Electromechanical Delay by Tissue Doppler Echocardiography in Obese Subjects

dc.authoridTaşolar, Hakan/0000-0002-1249-7240
dc.authoridAkaycan, Jülide/0000-0002-9174-6777
dc.authoridPekdemir, Hasan/0000-0002-4913-5120
dc.authoridCansel, Mehmet/0000-0003-4740-4371
dc.authorwosidErmis, Necip/A-5184-2018
dc.authorwosidTaşolar, Hakan/ABG-4466-2020
dc.authorwosidAkaycan, Jülide/ABI-2397-2020
dc.authorwosidPekdemir, Hasan/ABI-6096-2020
dc.authorwosidErmis, Necip/HJP-7061-2023
dc.authorwosidCansel, Mehmet/ABI-6324-2020
dc.contributor.authorYagmur, Julide
dc.contributor.authorCansel, Mehmet
dc.contributor.authorAcikgoz, Nusret
dc.contributor.authorErmis, Necip
dc.contributor.authorYagmur, Murat
dc.contributor.authorAtas, Halil
dc.contributor.authorTasolar, Hakan
dc.date.accessioned2024-08-04T20:32:45Z
dc.date.available2024-08-04T20:32:45Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOur aim was to evaluate whether atrial electromechanical delay measured by tissue Doppler imaging (TDI), which is an early predictor of atrial fibrillation (AF) development, is prolonged in obese subjects. A total of 40 obese and 40 normal-weight subjects with normal coronary angiograms were included in this study. P-wave dispersion (PWD) was calculated on the 12-lead electrocardiogram (ECG). Systolic and diastolic left ventricular (LV) functions, inter-and intra-atrial electromechanical delay were measured by TDI and conventional echocardiography. Inter-and intra-atrial electromechanical delay were significantly longer in the obese subjects compared with the controls (44.08 +/- 10.06 vs. 19.35 +/- 5.94 ms and 23.63 +/- 6.41 vs. 5.13 +/- 2.67 ms, P < 0.0001 for both, respectively). PWD was higher in obese subjects (53.40 +/- 5.49 vs. 35.95 +/- 5.93 ms, P < 0.0001). Left atrial (LA) diameter, LA volume index and LV diastolic parameters were significantly different between the groups. Interatrial electromechanical delay was correlated with PWD (r = 0.409, P = 0.009), high-sensitivity C-reactive protein (hsCRP) levels (r = 0.588, P < 0.0001). Interatrial electromechanical delay was positively correlated with LA diameter, LA volume index, and LV diastolic function parameters consisting of mitral early wave (E) deceleration time (DT) and isovolumetric relaxation time (IVRT; r = 0.323, P = 0.042; r = 0.387, P = 0.014; r = 0.339, P = 0.033; r = 0.325, P = 0.041; respectively) and, negatively correlated with mitral early (E) to late (A) wave ratio (E/A) (r = -0.380, P = 0.016) and myocardial early-to-late diastolic wave ratio (E-m/A(m)) (r = -0.326, P = 0.040). This study showed that atrial electromechanical delay is prolonged in obese subjects. Prolonged atrial electromechanical delay is due to provoked low-grade inflammation as well as LA enlargement and early LV diastolic dysfunction in obese subjects.en_US
dc.identifier.doi10.1038/oby.2010.195
dc.identifier.endpage783en_US
dc.identifier.issn1930-7381
dc.identifier.issn1930-739X
dc.identifier.issue4en_US
dc.identifier.pmid20829801en_US
dc.identifier.scopus2-s2.0-79953225146en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage779en_US
dc.identifier.urihttps://doi.org/10.1038/oby.2010.195
dc.identifier.urihttps://hdl.handle.net/11616/95287
dc.identifier.volume19en_US
dc.identifier.wosWOS:000288901400018en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofObesityen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectC-Reactive Proteinen_US
dc.subjectP-Wave Dispersionen_US
dc.subjectFibrillationen_US
dc.subjectRisken_US
dc.subjectIntraatrialen_US
dc.subjectDurationen_US
dc.subjectDiseaseen_US
dc.titleAssessment of Atrial Electromechanical Delay by Tissue Doppler Echocardiography in Obese Subjectsen_US
dc.typeArticleen_US

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