Randomised clinical trial of two bypass operations for unresectable cancer of the pancreatic head

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dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authoridKatz, Daniel/0000-0002-6495-0078
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidKayaalp, Cuneyt/AAH-1764-2021
dc.contributor.authorYilmaz, S
dc.contributor.authorKirimlioglu, V
dc.contributor.authorKatz, DA
dc.contributor.authorKayaalp, C
dc.contributor.authorCaglikulekci, M
dc.contributor.authorAra, C
dc.date.accessioned2024-08-04T20:12:18Z
dc.date.available2024-08-04T20:12:18Z
dc.date.issued2001
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To compare two different types of prophylactic gastric bypass in patients with cancer of the pancreatic head who were not suitable for curative resection. Design: Prospective study. Setting: University hospital, Turkey. Subjects: 44 patients with unresectable cancer of the pancreatic head without duodenal obstruction who presented between May 1995 and June 2000 who were randomised into 2 groups. Interventions: 22 patients had an antecolic, isoperistaltic gastrojejunostomy, jejunojejunostomy, and hepaticojejunostomy after cholecystectomy. The remaining 22 had a hepaticojejunostomy and antecolic, antiperistaltic gastrojejunostomy procedure after cholecystectomy. Main outcome measures: Mortality, morbidity, postoperative course, and survival. Results: There were no significant differences between the groups in the incidence of postoperative complications, time until restoration of oral diet, relaparotomy rate, late upper gastrointestinal bleeding, mortality, duration of hospital stay, and survival. The isoperistaltic operation took significantly longer than the antiperistaltic operation (p < 0.001) and there was less delayed gastric emptying in the antiperistaltic group but not significantly so. Both operations caused a significant lengthening in the postoperative gastric emptying time (p = 0.04 and p = 0.01, respectively). Conclusions: Both procedures are suitable for patients with unresectable carcinoma of the pancreatic head without impending duodenal obstruction. There was a trend towards better clinical results with the isoperistaltic procedure.en_US
dc.identifier.endpage776en_US
dc.identifier.issn1102-4151
dc.identifier.issue10en_US
dc.identifier.pmid11775730en_US
dc.identifier.scopus2-s2.0-0035662644en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage770en_US
dc.identifier.urihttps://hdl.handle.net/11616/93345
dc.identifier.volume167en_US
dc.identifier.wosWOS:000172759100009en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Asen_US
dc.relation.ispartofEuropean Journal of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpancreas canceren_US
dc.subjectcancer of the pancreatic headen_US
dc.subjectpalliative operationsen_US
dc.titleRandomised clinical trial of two bypass operations for unresectable cancer of the pancreatic headen_US
dc.typeArticleen_US

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