Risk factors of hepatitis B virus infection in Turkey: A population-based, case-control study

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dc.authoridBeytur, Ali/0000-0002-7870-3318
dc.authoridözer, ali/0000-0002-7144-4915
dc.authoridkoroglu, mehmet/0000-0001-8101-1104
dc.authorwosidBeytur, Ali/AAA-2823-2021
dc.authorwosidözer, ali/ABI-2209-2020
dc.authorwosidkoroglu, mehmet/HTN-0171-2023
dc.contributor.authorOzer, Ali
dc.contributor.authorYakupogullari, Yusuf
dc.contributor.authorBeytur, Ali
dc.contributor.authorBeytur, Leyla
dc.contributor.authorKoroglu, Mehmet
dc.contributor.authorSalman, Feyza
dc.contributor.authorAydogan, Fisun
dc.date.accessioned2024-08-04T20:35:47Z
dc.date.available2024-08-04T20:35:47Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Although the World Health Organization (WHO) classifies Turkey as a country with a moderate-high prevalence of hepatitis B virus (HBV) infection, there is little data on HBV transmission in this country. Objectives: To identify risk factors for HBV infection, we performed a retrospective case-control study between January 2007 and December 2009. Patients and Methods: Acute HBV patients and population controls were selected, and data from these groups were analyzed by logistic regression. method. Results: The study included 129 patients with acute HBV infection and 219 controls. Hemodialysis (OR:8.2, 95% Cl: 4.17-16.61, p < 0.05), having an HBsAg (+) spouse (OR: 4.3, 95% Cl:2.17-8.53, p < 0.05), living with an HBsAg (+) parent(s) (OR: 3.25, 95% CI:1.73-6.12, p < 0.05), and being male (OR: 1.34, 95% Cl: 0.82-2.21, p < 0.05) were independent risk factors that were potentially associated with HBV infection. More than one-third of female patients had a significantly higher risk (34.5% vs. 13.5%, p < 0.05) of acquiring HBV from their sexual partners. Hemodialysis was the most frequent risk factor (46.9% vs. 20%, x(2) = 10.45, p < 0.05) for patients aged over 31 years, and living with HBsAg (+) parents was a significantly higher risk factor (28.8% vs. 10.2%, x(2) = 6.15, p < 0.05) that is more likely to lead to HBVin patients aged under 30 years. Conclusions: This study suggests that persons in Turkey who undergo hemodialysis are at high risk for acquiring HBV. Having an HBsAg (+) spouse (sexual transmission) or living with HBsAg (+) parents (household transmission) are significant risk factors for HBV transmission. Vaccination appears to be better preventive method against the spread of HBV. (C) 2011 Kowsar M.P.Co. All rights reserved.en_US
dc.identifier.endpage268en_US
dc.identifier.issn1735-143X
dc.identifier.issue4en_US
dc.identifier.pmid22087152en_US
dc.identifier.scopus2-s2.0-84857834425en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage263en_US
dc.identifier.urihttps://hdl.handle.net/11616/95591
dc.identifier.volume11en_US
dc.identifier.wosWOS:000290239300006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBaqiyatallah Research Centeren_US
dc.relation.ispartofHepatitis Monthlyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatitis B virusen_US
dc.subjectTransmissionen_US
dc.subjectRisk factoren_US
dc.titleRisk factors of hepatitis B virus infection in Turkey: A population-based, case-control studyen_US
dc.typeArticleen_US

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