Factors affecting survival of hospitalised patients with COPD

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dc.authoridGulbas, Gazi/0000-0002-9435-8307
dc.authoridHacievliyagil, Suleyman Savas/0000-0002-2572-1870
dc.authoridMutlu, Levent Cem/0000-0002-3535-5704
dc.authoridGunen, Hakan/0000-0001-6631-4457
dc.authorwosidGulbas, Gazi/ABI-5182-2020
dc.authorwosidMutlu, Levent Cem/HII-6048-2022
dc.authorwosidHacievliyagil, Suleyman Savas/ABI-7307-2020
dc.authorwosidŞahin, İbrahim/HHY-8303-2022
dc.authorwosidMutlu, Levent Cem/AAZ-5186-2020
dc.authorwosidGunen, Hakan/HKV-9202-2023
dc.contributor.authorGunen, H
dc.contributor.authorHacievliyagil, SS
dc.contributor.authorKosar, F
dc.contributor.authorMutlu, LC
dc.contributor.authorGulbas, G
dc.contributor.authorPehlivan, E
dc.contributor.authorSahin, I
dc.date.accessioned2024-08-04T20:14:54Z
dc.date.available2024-08-04T20:14:54Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractFactors determining in-hospital mortality and long-term survival of patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are not precisely understood. The aim of the present study was to assess the parameters related to in-hospital mortality and long-term survival after hospitalisation of patients with AECOPD. Clinical and epidemiological parameters on admission in 205 consecutive patients hospitalised with AECOPD were prospectively assessed. Patients were followed-up for 3 yrs. Factors determining short- and long-term mortality were analysed. In total, 17 patients (8.3%) died in hospital. In-hospital mortality was significantly associated with lower arterial oxygen tension (Pa,O-2), higher carbon dioxide arterial tension, lower arterial oxygen saturation and longer hospital stay. The overall 6-month mortality rate was 24%, with 1-, 2- and 3-yr mortality rates of 33%, 39% and 49%, respectively. Cox regression analysis revealed that long-term mortality was associated with longer disease duration (relative risk (RR)=1.158), lower albumin (RR=0.411), lower Pa,O-2 (RR=0.871) and lower body mass index (RR=0.830). When the model was run for the time elapsed since first hospitalisation, it also appeared as statistically significant (RR=1.195). These findings show that patients hospitalised with acute exacerbations of chronic obstructive pulmonary disease have poor short- and long-term survival. Prediction of survival status may be enhanced by considering arterial oxygen tension, albumin, body mass index, disease duration and time elapsed since the first hospitalisation.en_US
dc.identifier.doi10.1183/09031936.05.00024804
dc.identifier.endpage241en_US
dc.identifier.issn0903-1936
dc.identifier.issn1399-3003
dc.identifier.issue2en_US
dc.identifier.pmid16055870en_US
dc.identifier.scopus2-s2.0-23144436700en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage234en_US
dc.identifier.urihttps://doi.org/10.1183/09031936.05.00024804
dc.identifier.urihttps://hdl.handle.net/11616/94034
dc.identifier.volume26en_US
dc.identifier.wosWOS:000230874000009en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherEuropean Respiratory Soc Journals Ltden_US
dc.relation.ispartofEuropean Respiratory Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectchronic obstructive pulmonary diseaseen_US
dc.subjectin-hospitalen_US
dc.subjectlong-term survivalen_US
dc.subjectmortalityen_US
dc.titleFactors affecting survival of hospitalised patients with COPDen_US
dc.typeArticleen_US

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