Experience with Levamisole in Children with Frequently Relapsing and Steroid-Dependent Nephrotic Syndrome

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dc.authorwosidTabel, Yilmaz/AAF-9801-2020
dc.contributor.authorTabel, Yilmaz
dc.date.accessioned2024-08-04T20:31:18Z
dc.date.available2024-08-04T20:31:18Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this manuscript; we aimed to report our experience with levamisole in frequently relapsing and/or steroid-dependent idiopathic nephrotic syndrome of childhood. Classical treatment option of idiopathic nephrotic syndrome of childhood is steroid. Although 90% of patients respond to steroid treatment, 80-90% of patients relapse during follow-up and 25-45% of patients become frequent relapser, half of which progresses to steroid-dependent. Steroid-dependent and frequent relapser children are under risk of steroid toxicity. Successful treatment with levamisole is reported in the current literature, when steroids fail and/or toxicity occurs. According to these findings, we treated three frequent relapser and two steroid-dependent nephrotic syndrome patients with levamisole for six months. Other than one of the frequent relapsers who did not respond, number of the attacks and cumulative steroid dosage significantly decreased in all. As a result; we think that using cheap and effective levamisole with less adverse effects in frequent relapser and steroid-dependent nephrotic syndrome increases the remission rate and duration, and also prevents the adverse effects of other immunosuppressives.en_US
dc.identifier.endpage248en_US
dc.identifier.issn1301-3149
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-70349156434en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage245en_US
dc.identifier.urihttps://hdl.handle.net/11616/94872
dc.identifier.volume25en_US
dc.identifier.wosWOS:000261815500016en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherEkin Tibbi Yayincilik Ltd Sti-Ekin Medical Publen_US
dc.relation.ispartofTrakya Universitesi Tip Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChilden_US
dc.subjectsteroid-dependent nephrotic syndromeen_US
dc.subjectlevamisoleen_US
dc.subjectfrequently relapsingen_US
dc.titleExperience with Levamisole in Children with Frequently Relapsing and Steroid-Dependent Nephrotic Syndromeen_US
dc.typeArticleen_US

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