The comparison of nail and serum trace elements in patients with epilepsy and healthy subjects

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dc.authoridIlhan, Nevin/0000-0002-0208-8929
dc.authoridİLHAN, NECİP/0000-0001-9997-0418;
dc.authorwosidIlhan, Nevin/J-5761-2017
dc.authorwosidİLHAN, NECİP/V-8908-2018
dc.authorwosidÖZEROL, ELİF/AAA-6707-2021
dc.contributor.authorIlhan, A
dc.contributor.authorÖzerol, E
dc.contributor.authorGüleç, M
dc.contributor.authorIsik, B
dc.contributor.authorIlhan, N
dc.contributor.authorIlhan, N
dc.contributor.authorAkyol, Ö
dc.date.accessioned2024-08-04T20:13:36Z
dc.date.available2024-08-04T20:13:36Z
dc.date.issued2004
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe objective of this prospective study was to determine the levels of manganese (Mn), copper (Cu), and zinc (Zn) levels in both nail and serum from patients with epilepsy. For this purpose, levels of these elements were measured in 31 patients with epilepsy and 19 healthy subjects. Element analyses were carried out by atomic absorption spectrophotometer (AAS). Increased Mn levels were detected in nail of patients with epilepsy compared to healthy controls (P<.008). The main nail Zn and Cu levels were found to be unchanged in epileptic patients compared to control subjects. There were no significant differences in serum Mn and Zn levels between epileptic patients and control subjects. However, there was a statistically significant increase in serum Cu levels in patients with epilepsy in comparison with control group (P<.009). Our results demonstrate that some trace element levels may vary in epileptic patients, and because of the more stable status, the analysis of these element levels in some tissues such as nail might be superior to serum analysis. (C) 2003 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.pnpbp.2003.09.025
dc.identifier.endpage104en_US
dc.identifier.issn0278-5846
dc.identifier.issn1878-4216
dc.identifier.issue1en_US
dc.identifier.pmid14687863en_US
dc.identifier.scopus2-s2.0-0346995103en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage99en_US
dc.identifier.urihttps://doi.org/10.1016/j.pnpbp.2003.09.025
dc.identifier.urihttps://hdl.handle.net/11616/93708
dc.identifier.volume28en_US
dc.identifier.wosWOS:000187938800013en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofProgress in Neuro-Psychopharmacology & Biological Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectepilepsyen_US
dc.subjectnailen_US
dc.subjectserumen_US
dc.subjectcopperen_US
dc.subjectzincen_US
dc.subjectmanganeseen_US
dc.titleThe comparison of nail and serum trace elements in patients with epilepsy and healthy subjectsen_US
dc.typeReview Articleen_US

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